Stroke Prevention and Future Treatments Will Save Lives
There may be a health story behind Ariel Sharon’s recent stroke. His
doctors recommended Sharon start a diet and exercise program. This may
be the right approach to help prevent strokes. The meal he had just
before the stroke included hamburgers, steak, lamb chops, shish kebab
and two slices of chocolate cake.
Could this meal have been the reason for the stroke? No one knows for
sure, but diet can lead to various problems that can lead to a stroke.
For those that have already had a stroke it is even more important to
lead a healthy lifestyle.
There are some
things you can do to prevent a stroke. The first thing a person should
do is quit smoking if they smoke. Of course diet and regular exercise
will reduce the risk of a stroke. Also keep diabetes and blood pressure
There is some new research that my help save lives during a stroke.
John Hopkins scientists have discovered a method to prevent brain damage
during a stroke. The brain cells die because of lack of oxygen. The
researchers have found a nerve receptor that acts as a switch killing
By studying mice they were able to demonstrate that a protein on the
surface of the nerve cells, called EP1 receptors, act as a switch that
turns off when a compound known as ONO-8713 turns it off. The cell then
Current treatments include COX-2 inhibitors that can be dangerous.
These drugs block the ability of the enzyme cyclooxygenase-2 (COX-2) to
make prostaglandin E2 (PGE2). It appears PGE2 causes brain damage
following a stroke by binding to the EP1 nerve cells.
John Hopkins researchers believe that activity blocking the PGE2
directly rather than inhibiting COX-2 may be a better treatment. The
innovations-report website reports that Sylvain Doré, Ph.D., an
associate professor in the departments of Anesthesiology and Critical
Care Medicine and Neuroscience at The Johns Hopkins University School of
Medicine, said “A lot of the previous findings kept bringing us back to
PGE2 and its receptors, So we investigated whether it’s possible to
block the EP1 receptor so PGE2 couldn’t trigger toxic effects”.
The mice that received the EP1 stimulator ONO-DI-004 suffered more than
28% greater brain damage than the control group. Mice that were treated
with the EP1 blocker ONO-8713 had only about 71% of the brain damage as
the controls. The “ONO-8713 works specifically at that receptor” that
causes the brain damage.
Let’s hope a better treatment for stroke is implemented quickly.
According to the American Academy of Family Physicians “Every year,
approximately 500,000 Americans have a first stroke, and approximately
20 percent die within 30 days.”
We recently published a similar article concerning a new possible
treatment developed in Italy. This research found that the
IKK2 Protein may Prevent Brain Damage Due to Stroke.
By Dan Wilson
Best Syndication Staff Writer
Stroke Treatment Books
Keywords and misspellings: stroak strok prevention
prevension treetment treatment