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New Study reveals why H5N1 bird flu in Humans so Deadly

New Study reveals why H5N1 bird flu in Humans so Deadly

Blocked airways

There is new understanding as to why the bird flu is so deadly to humans.  The H5N1 virus triggers cytokines and chemokines which are inflammatory proteins at a ratio of 10 times more than a common flu. 

The experiments were conducted on human cells with the h5N1 virus and compared against the H1N1 common flu strain.  Because of the dramatic increase of these inflammatory proteins it can cause the air passages to inflame making it hard to breathe.  It also increases respiratory distress and pneumonia. 

Current statistics of worldwide infected numbers of human cases of the H5N1 bird flu has reached 125 with 64 dying.  

 

Published in the online version of Respiratory Research on November 11th, Michael Chan from the University of Hong Kong and other researchers from Vietnam studied how the levels of cytokines and chemokines increased when being exposed to the H5N1 virus.

The report concluded with the following statement “The H5N1/97 and H5N1/04 subtype influenza A viruses are more potent inducers of pro-inflammatory cytokines and chemokines in primary human respiratory epithelial cells than subtype H1N1 virus. We suggest that this hyper-induction of cytokines may be relevant to the pathogenesis of human H5N1 disease.”

 

The researchers believe that these particular proteins may play a part in the origination and development of the deadly H5N1 infections in humans.  The inflammation of the air passages are the deadliest part of the H5N1 virus.

Related articles:
Spanish Flu Pandemic of 1918 was Caused by Bird to Human Transmission

H5N1 strain Avian Bird Flu infects 4 year old Boy
H5N1 strain Avian Bird Flu found in Romania and Turkey


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By Nicole Wilson
Best Syndication Staff Writer

 

 

Common keywords and misspellings: H5N1 virus bird flu pandemic avian flu infection disease repiratory study


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Copyright 2005 Best Syndication                                            Last Updated Saturday, July 10, 2010 09:46 PM