New Study reveals why
H5N1 bird flu in Humans so Deadly
There is new understanding as to why
the bird flu is so deadly to humans. The H5N1 virus triggers cytokines
and chemokines which are inflammatory proteins at a ratio of 10 times
more than a common flu.
The experiments were conducted on
human cells with the h5N1 virus and compared against the H1N1 common flu
strain. Because of the dramatic increase of these inflammatory proteins
it can cause the air passages to inflame making it hard to breathe. It
also increases respiratory distress and pneumonia.
Current statistics of worldwide
infected numbers of human cases of the H5N1 bird flu has reached 125
with 64 dying.
Published in the online version of
Respiratory Research on November 11th, Michael Chan from the
University of Hong Kong and other researchers from Vietnam studied how
the levels of cytokines and chemokines increased when being exposed to
the H5N1 virus.
The report concluded with the
following statement “The H5N1/97 and H5N1/04 subtype influenza A viruses
are more potent inducers of pro-inflammatory cytokines and chemokines in
primary human respiratory epithelial cells than subtype H1N1 virus. We
suggest that this hyper-induction of cytokines may be relevant to the
pathogenesis of human H5N1 disease.”
The researchers believe that these
particular proteins may play a part in the origination and development
of the deadly H5N1 infections in humans. The inflammation of the air
passages are the deadliest part of the H5N1 virus.
Best Syndication Staff Writer
Common keywords and misspellings: H5N1 virus bird flu
pandemic avian flu infection disease repiratory study
Copyright 2005 Best Syndication Last Updated
Saturday, July 10, 2010 09:46 PM