GAKIC, chemically known as
glycine-l-arginine-alpha-ketoisocaproic acid, may be new to
Bodybuilders, athletes, and sports enthusiasts, though it has been
in development for 8 years already and many studies have been done
on this supplement. It's not like creatine, a stimulant or a generic
pre-workout supplement. GAKIC is a pre-workout musclebuilding
Many studies have been done on this
supplement and some have been published in publications such as
Medicine & Science in Sports & Exercise. In one study, GAKIC
supplementation significantly increased the total muscle work
performed during resistance training by an average of 10.5 percent
during the first 15 minutes. In the same study, GAKIC
supplementation was shown to significantly increase fatigue
resistance by up to an average of 28 percent when compared with the
To get bigger, the human body
has to pass new barriers by blasting through the body's normal
fatigue threshold, also known as “failure”. After years of
scientific scrutiny, researchers believe that one of the key
mechanisms responsible for the performance-enhancing effects of
GAKIC is the removal of the fatigue toxin ammonia, which can
interfere with normal muscle metabolism and generally limit muscular
power output. With decreased fatigue toxin levels, the body can
perform more work. This can eventually translate into better
muscular gains as training intensity and strength improve over time.
In layman’s terms, GAKIC is designed to help the body
deal with metabolic fatigue by delaying the moment of failure -
helping to get 1, 2, or even 3 more reps in. Since GAKIC works
immediately, all that is needed is to take it before training.
There's no loading, cycling, or maintenance phases.
What's in GAKIC is chemically known as
Glycine is a nonessential amino acid,
meaning your body's cells can synthesize sufficient amounts of it to
meet physiological requirements. Studies show that production of
growth hormone (one of the most important musclebuilding hormones)
increases in a dose-dependent manner with glycine supplementation.
Another thing about glycine is that when it's combined with arginine
(as it is in GAKIC), it has the potential to increase endogenous
Arginine plays an important role in
many bodily functions including the removal of ammonia from the
body, immune function, and the release of hormones. The body also
uses it to produce nitric oxide, which relaxes blood vessels.
Alpha-ketoisocaproate represents the
“KIC” in GAKIC. KIC is a branched-chain keto acid (BCKA) that has
anti-catabolic effects meaning it can help prevent muscle loss.
BCKAs also aid in a muscle's energy production while helping to
remove ammonia. Buildups of ammonia are common during intense
training sessions, and have been known to play a part in fatigue.
How Gakic Works
There are two types of failure: that
which occurs due to neurological issues and that which occurs due to
metabolic issues. The former occurs with lower rep training, whereas
the latter occurs with moderate to high-rep training. In the example
above, metabolic fatigue sets in due to the build-up of various
metabolic by-products which negatively affects exercise performance
and inhibits some aspects of the muscle's contractile machinery.
GAKIC helps your body deal with this metabolic fatigue and thus
delays this moment of failure.
Does Gakic contain Creatine?
No. GAKIC is not a creatine
supplement. Creatine increases the regeneration of a primary muscle
fuel source called adenosine triphosphate (ATP). GAKIC works at the
muscle fiber level via different metabolic mechanism than creatine.
One of GAKIC's jobs is to remove fatigue toxins toxins that
prevent your muscles from making more ATP.
GAKIC is available in either powder or caplet form and can be found at
online retailers such as