Alzheimer's Disease Gene identified that Increases Risk

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[Best Syndication News] Researchers have found a gene, MTHFD1L, that they believe is associated with an increased risk for developing late-onset Alzheimer's disease. The researchers will be presenting their findings at the American Academy of Neurology’s 62nd Annual Meeting in Toronto, which is running from April 10 – 17, 2010.

Researchers looked at 2,269 people that were diagnosed with late-onset Alzheimer's Disease for a common gene variation. They compared the Alzheimer's patients genetics against the genes of 3,107 people that don't have the disease. They searched for matches in the whole genome instead of just isolated areas.

They found that the Alzheimer's disease risk was associated twice the risk when a person had a variation in the MTHFD1L gene. This gene is known to be involved with regulating homocysteine levels, which the researchers point out that high homocysteine levels are a strong risk factor for developing Alzheimer's disease. MTHFD1Lcould also possibly be associated with increase a persons risk for coronary artery disease.

By: N Wilson



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