Diabetic Retinopathy – Two Therapies could slow down Eye Disease Blindness

Diabetic Retinopathy – Two Therapies could slow down Eye Disease Blindness

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(Best Syndication News) - The Action to Control Cardiovascular Risk in Diabetes (ACCORD) Eye Study, which was funded in part by the National Institutes of Health, have found two therapies that might slow down the progression of diabetic retinopathy. This eye disease is the most common reason for working adults to go blind or having significant vision loss in America. The study results were published in the June 29th online edition of the New England Journal of Medicine (NEJM) and will also be presented at the 70th Scientific Sessions of the American Diabetes Association.

The ACCORD study included 10,251 adults with type 2 diabetes who were at especially high risk for heart attack, stroke or cardiovascular death. The study looked into three different intensive treatment plans that were being tested to lower the risk for cardiovascular risk factors caused by diabetes. They had a subgroup involved in the Eye Study which included 2,856 participants from the ACCORD study which they documented the diabetic retinopathy progression over a four year time period.

The researchers found that intensive blood sugar control treatment reduced the diabetic retinopathy eye disease from progressing. In addition they also saw therapy with both a fibrate and a statin also slowed down the eye disease better than if they took only statins. The Fenofibrate (fibrate) was used to lower the triglycerides and increase the “good” HDL cholesterol levels while the simvastatin (statin) was used to lower the “bad” LDL cholesterol. The researchers also found that intensive blood pressure control did not show any benefit for slowing down diabetic retinopathy compared to those that had regular blood pressure control.

The researchers warn that while the intensive glycemic control is beneficial for slowing down the diabetic retinopathy, having glucose level at near normal levels showed an increased risk of death and increased the chances of having dangerous hypoglycemia. They are recommending that patients and their doctors consider these risk factors when developing a treatment plan.



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