Tangerines contain a Flavonoid that might protect against Type 2 Diabetes and Obesity

Tangerines contain a Flavonoid that might protect against Type 2 Diabetes and Obesity

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(Best Syndication News) - Tangerines have a flavonoid called Nobiletin that could prevent obesity and also protect a person from developing type 2 diabetes said a recent study published in the journal Diabetes. Researchers at the University of Western Ontario investigated mice who were given the Nobiletin and saw several benefits that could prompt future studies with people. The research was conducted by Murray Huff, a vascular biology scientist at the Schulich School of Medicine & Dentistry, and Erin Mulvihill, a PhD student.

There were two groups of mice. Both mice were fed the “western” high fat diet with simple sugars which would give them indicators associated with metabolic syndrome. Then one group was given the Nobiletin in addition to their "western" diet while the other did not get the supplement.

The group that didn't get the Nobiletin showed high cholesterol levels, high triglycerides, increased levels of insulin and glucose in the blood, and a fatty liver.

The group the received the Nobiletin in addition to the “western” diet did not have the increases in the blood levels and they gained weight normally. In addition to these benefits, the mice that got the Nobiletin also had more sensitive insulin. The researchers said that Nobiletin protected the mice from atherosclerosis or clogged arteries from plaque buildup. Atherosclerosis is known to increase the risk for having a stroke or a heart attack. In addition, the Nobiletin prevented fat in the liver from developing by keeping the liver from manufacturing fat it and helping the body burn excess fat.

Two years prior, Murray Huff, discovered grapefruit's flavonoid called Naringenin, that also showed benefits for preventing against obesity and metabolic syndrome. However, Huff said that Nobiletin is ten times more potent for its protective benefits when compared with Naringenin. With Nobiletin, he added, it had the potential to protect against artherosclerosis as well.

Future research in humans would need to be conducted to further understand the potential benefits of the flavonoids. The Nobiletin study was funded by Canada's Heart and Stroke Foundation of Ontario, and there was an additional grant which was supplied by the Pfizer Canada Cardiovascular Research Program.

BY: N Wilson



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