Soy Isoflavone Supplement did not help with Menopause Hot Flashes or with Bone Density

Supplements - credit: BSN

(Best Syndication News) - A five-year study found that menopausal women did not benefit from taking soy-isoflavone supplement tablets. The women who took the soy supplement, had slightly more hot flashes reported. Additionally, there were not any differences in bone density tests compared to the placebo supplement group. The study results were first reported in the August 8, 2011, issue of the JAMA’s Archives of Internal Medicine.

The article explains that during the early menopause stage, women suffer from quick bone density reduction, sleep problems, hot flashes, vaginal dryness, and other symptoms. Previously estrogen therapy was used to treat these symptoms, but risks often offset the help with this treatment method. The risks with hormone therapy treatments have caused many women to look for alternative treatments and remedies to relieve menopausal symptoms. The researchers wanted to see if soy-derived supplements would offer similar menopause relief relative to the estrogen therapy.

Silvina Levis, M.D., of the Miami Veterans Affairs Healthcare System and Miller School of Medicine, University of Miami, conducted the soy isoflavone study along with other colleagues. The randomized controlled trial involved 248 women participants between July 2004 and March 2009. The women were within five years of menopause ranging between 45 to 60 years old. The researchers measured the women’s bone mineral density T score to determine at the start of the study that the women were within a normal rating. There were 126 women that were given the Soy supplements; the other 122 were given a placebo tablet.

At the two-year follow-up, the bone density measurements in the two groups were not significantly different. Menopausal symptoms were similar in both the start and the end of the study in both groups, except with hot flash symptoms. The soy isoflavone group had a higher amount of hot flashes at the end of the study. The soy group had reported 48.8 percent hot flash symptoms compared to 31.7 percent in the placebo group. Although not a significant finding, more women in the soy group (31.2 percent) reported constipation compared to the placebo group (20.6 percent).

The conclusion from this study was that 200 mg of soy isoflavone tablets taken once daily did not help with menopause symptoms or with bone loss prevention or lower bone turnover rates.

By: Marsha Quinn

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