Osteoporosis rates higher with Early Menopause

credit: National Cancer Institute Daniel Sone (Photographer) - PD

(Best Syndication News) - A new study found that early menopause was associated with twice the chance of having osteoporosis later in life. The Swedish research was published in the BJOG: An International Journal of Obstetrics and Gynaecology.

In the Swedish Malmo Perimenopausal Study, 390 white northern European women participated in the observational study starting back in 1977 when they were 48 years old. The women were categorized into one group who started menopause before 47 and the other group who started menopause at 47 or later.

The women had a bone mineral density test at the beginning of the study and again when they were 77 years old. When the later test was conducted, 92 were dead and 298 were still alive. Out of the 298 participants, 100 had relocated or did not participate in the study. There were 198 women that the researchers were able to measure and follow up on when they were 77 years old.

The results for women at age 77 showed that 56 percent of the early menopause women had developed osteoporosis, while only 30 percent of the women with late menopause had osteoporosis.

Additionally, the researchers found that the early menopause group of women with osteoporosis had a higher risk of fragility fracture and of mortality. The death rate was 52.4 percent in the early menopause group, while the late menopause group’s mortality rate was only 35.2 percent. The women in the early menopause group had a fracture occurrence rate of 44.3 percent compared to the late menopause group’s fracture rate of 30.7 percent.

The main author of the study, Ola Svejme, orthopaedic surgeon at the Skåne University Hospital, Malmo, Sweden said, "The results of this study suggest that early menopause is a significant risk factor for osteoporosis, fragility fracture and mortality in a long-term perspective. To our knowledge, this is the first prospective study with a follow-up period of more than three decades."

By: Marsha Quinn
Health Reporter



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