Type 2 - diabetes

‘Extreme Makeover: Weight Loss Edition’ premieres tonight on ABC

Extreme Makeover - Weight Loss Edition - ABC

see sneak peek below

(Best Syndication News) - A new reality TV show on ABC called ‘Extreme Makeover: Weight Loss Edition’ will be premiering tonight at 10/9c. This is new competition for NBC’s popular ‘The Biggest Loser’ TV show which just wrapped up its latest season. Even though the shows both focus on dramatic weight loss transformations, they are both very different on how they present their shows.

The ‘Extreme Makeover: Weight Loss Edition’ will be different from ‘The Biggest Loser.’ Instead of having competing weight loss and eliminations, this show tracks the weight loss of eight participants over a year’s time. The coach is Chris Powell who has a degree in Exercise Science. Instead of having the participants move into a ranch, Powell moves into the participants’ homes.

Obesity Epidemic - Could niacin be making us fat?

credit: National Cancer Institute PD

credit: National Cancer Institute

(Best Syndication News) - Niacin is supplemented in many grain products in the US, which may be promoting overeating and contributing to the obesity epidemic. Researchers from China investigated glucose levels and insulin resistance when children had excess consumption of nicotinamide, which is a form of vitamin B3. They found nicotinamide supplementation could be a factor in obesity increasing in children. The study was published in the May 21, 2010 issue of the World Journal of Gastroenterology.

The Chinese researchers had concluded that nicotinamide is involved in oxidative stress and promoted an increased appetite. With a glucose and niacin loading test, the children showed insulin resistance at the first measure, and then at the second measure there was hypoglycemia. The hypoglycemia is low blood sugar, which causes a person to get hungry. Insulin resistance is associated with Type 2 diabetes. The researchers suspect that the excess niacin in the diets of children in the US is a major factor for the rising obesity rate.

Master Switch that controls fat found

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(Best Syndication News) Researchers at the King’s College in London and the University of Oxford found a gene that controls fat cells. It was already known that the KLF14 gene is linked to type-2 diabetes and cholesterol levels, but researchers now know it controls much more.

They say there is an “association” between the KLF14 gene and the expression levels of multiple distant genes found in fat tissue. The KLF14 gene is a “master switch”. It controls the body-mass index (obesity), cholesterol, insulin and glucose levels.

The metabolic traits are inherited from the mother. “The copy of KLF14 from the father is switched off, meaning that the copy from the mother is the active gene,” the King’s College reported Monday.

Type 2 Diabetes – Tradjenta (linagliptin) gets FDA approval

prescription medication

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(Best Syndication News) - A new prescription medication Tradjenta (linagliptin) has gained the US Food and Drug Administration's (FDA) approval for the treatment of adult Type 2 diabetes. Tradjenta can be used alone or with other treatments to help lower blood glucose levels. Boehringer Ingelheim Pharmaceuticals Inc. are the marketers of Tradjenta.

The way Tradjenta helps to improve blood glucose levels is by blocking the enzyme dipeptidyl peptidase-4 or DPP-4. This allows hormones levels that stimulate the release of insulin to increase after a meal and thereby reducing blood glucose levels.

There were eight double-blind, placebo-controlled clinical studies conducted that involved around 3,800 Type 2 diabetes patients. The results showed better blood glucose control compared to those taking a placebo.

Tangerines contain a Flavonoid that might protect against Type 2 Diabetes and Obesity

Tangerines contain a Flavonoid that might protect against Type 2 Diabetes and Obesity

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(Best Syndication News) - Tangerines have a flavonoid called Nobiletin that could prevent obesity and also protect a person from developing type 2 diabetes said a recent study published in the journal Diabetes. Researchers at the University of Western Ontario investigated mice who were given the Nobiletin and saw several benefits that could prompt future studies with people. The research was conducted by Murray Huff, a vascular biology scientist at the Schulich School of Medicine & Dentistry, and Erin Mulvihill, a PhD student.

There were two groups of mice. Both mice were fed the “western” high fat diet with simple sugars which would give them indicators associated with metabolic syndrome. Then one group was given the Nobiletin in addition to their "western" diet while the other did not get the supplement.

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