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Genetics and Stem Cells

Breast Cancer Cells Transformed into Stem Cells via Radiation Treatments

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Radiation Therapy

(Best Syndication News) Researchers say that radiation treatments can turn cancer tumor cells into “treatment resistant breast cancer stem cells.”

Researchers from the UCLA Department of Radiation Oncology at the Jonsson Comprehensive Cancer Center, say that if they can stop the transformation of these cancer cells into stem cells, radiation treatments could be even more effective.

Although half of the tumor cells are killed-off during radiation treatments, some that remain morph into these stem cells that are resistant to the treatments, according to Dr Frank Pajonk, who is also a scientist with the Eli and Edythe Broad Center of Regenerative Medicine at UCLA.

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Scientists investigate new ways to combat constantly changing Flu Virus

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(Best Syndication News) A University of Georgia research team is gaining headway in their attempt to understand the constantly evolving influenza virus. Ralph Tripp, a Georgia Research Alliance Eminent Scholar and Chair of Animal Health Vaccine Development in the UGA College of Veterinary Medicine, says that interfering with the way viruses replicate may provide a way to treat the flu.

Viruses replicate by attaching themselves to a host cell, and turning that cell into a factory. Tripp says that influenza binds with sugars found on the surface of host cells in the lung and respiratory tract. The virus then injects its genetic information into the nucleus of the cell and virus replication begins.

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Mesothelioma - Genetic Mutation increases Cancer Risk

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(Best Syndication News) - Researchers believe they have found a genetic link between developing mesothelioma and Melanoma of the eye. Mutations in the BAP1 gene is associated with an increased risk for developing these two cancers. The study is in the online August 28, 2011 edition of Nature Genetics.

The study was funded by the National Cancer Institute (NCI) and was conducted by researchers from the University of Hawaii Cancer Center, Honolulu, and Fox Chase Cancer Center, Philadelphia.

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Master Switch that controls fat found

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(Best Syndication News) Researchers at the King’s College in London and the University of Oxford found a gene that controls fat cells. It was already known that the KLF14 gene is linked to type-2 diabetes and cholesterol levels, but researchers now know it controls much more.

They say there is an “association” between the KLF14 gene and the expression levels of multiple distant genes found in fat tissue. The KLF14 gene is a “master switch”. It controls the body-mass index (obesity), cholesterol, insulin and glucose levels.

The metabolic traits are inherited from the mother. “The copy of KLF14 from the father is switched off, meaning that the copy from the mother is the active gene,” the King’s College reported Monday.

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Reprogrammed Sperm Cells Could Cure Type 1 Diabetes

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(Best Syndication News) Scientists from the Georgetown University Medical Center (GUMC) say that men with type-1 diabetes may be able to grow their own insulin producing cells.

Researchers reported their findings to an audience at the 50th annual meeting of the American Society of Cell Biology conference in Philadelphia. They found that human spermatogonial stem cells (SSCs) extracted from testicular tissue can change into insulin-secreting beta islet cells.

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