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Genetics and Stem Cells

Colon Cancer Gene Found – Scientists Begin To Understand The Link With Obesity

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Colon Cancer Gene Found – Scientists Begin To Understand The Link With Obesity

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(Best Syndication News) Researchers in the United States report that there is a link between a gene variation and colon cancer. It is hoped that a screening or diagnostic tool can be developed.

Previous studies have found that there is an association between obesity and colorectal cancer. If a person has a gene for a protein hormone that is secreted by fat cells he or she is at a reduced risk for colorectal cancer. The hormone, Adiponectin which is secreted by the fat tissue, is inversely proportional to obesity and high levels of insulin.

First Study

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Molecule Prevents Heart Damage During Attack and Surgery – Also Helps Asian Patients Who Do Respond TO Nitroglycerin

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Molecule Prevents Heart Damage During Attack and Surgery – Also Helps Asian Patients Who Do Respond TO Nitroglycerin

Damaged Heart Muscle

(Best Syndication News) American scientists have found a molecule that can minimize damage to the heart after a heart attack and during heart surgery. The compound can also be used to treat 40 percent of people of East Asian descent who carry a mutated form of the ALDH2 enzyme who do not respond to nitroglycerin and other cardiovascular treatments.

The ALDA-1 Molecule

The scientists from the Stanford and Indiana universities schools of medicine stumbled upon the molecule while investigating how ethyl alcohol (ethanol or drinking alcohol) protects muscle during a heart attack. They may have also found a way to reduce chest pain and the heart attack damage among millions of people of East Asian descent who are genetically unable to respond to nitroglycerin.

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Scientists Find More Genes Associated With Cancer – May Lead To Treatments For All Forms Including Brain and Pancreatic Cancers

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Scientists Find More Genes Associated With Cancer – May Lead To Treatments For All Forms Including Brain and Pancreatic Cancers

Microarray Chip

(Best Syndication News) Although there are several causes of cancer, researchers today announced major breakthroughs in determining the genetic relationship of the disease. The Cancer Genome Atlas (TCGA) Research Network sponsored by the National Institute of Health (NIH) is playing a central role in finding the genetic pathways associated with all sorts of cancers.

Research conducted by the Johns Hopkins Kimmel Cancer Center was published today in the Sept. 5, 2008, issue of Science Express. Research conducted by the Dana-Farber Cancer Institute was published in the Journal Nature. Both articles describe their work involved in finding an array of broken, missing, underactive and overactive genes that can lead to cancer.

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Scientists Convert Pancreatic Cells Rather Than Use Embryonic Stem Cells – Possible Treatment Or Cure For Type-1 Diabetes –Genes

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Scientists Convert Pancreatic Cells Rather Than Use Embryonic Stem Cells – Possible Treatment Or Cure For Type-1 Diabetes –Change 3 Genes

Melton

(Best Syndication News) Scientists have been able to change the function of non-insulin producing adult pancreatic cells into insulin producing beta cells using viruses to transport just three genes. Although the experiments were done on mice, the investigators are excited about the potential of the concept and its use on humans. (see videos below)

No Need For Stem Cells

The technique does not involve embryonic stem cells. The researchers were able to reprogram adult pancreatic cells using viruses as a “shuttle”. They changed the functional identity of the adult cells and the process was quick, according to their report. The method is sometimes referred to as “adult cell switching” or “lineage switching”.

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Brown Fat Burns White Fat – BMP-7 Protein Used To Treat Bone Injuries May Be Used For Weight Loss Diets

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Brown Fat Burns White Fat – BMP-7 Protein Used To Treat Bone Injuries May Be Used For Weight Loss Diets

BMP-7

(Best Syndication News) Researchers studying a protein called BMP-7 (Bone Morphogenetic Protein 7) that promotes bone growth discovered that it can also promote the development of brown fat. There are two types of fat: brown and white. The brown fat is good and can help burn the white fat.

The scientists found brown fat bundled inside the muscle fibers of obese-resistant mice. “We hope this study can be translated into applications to help treat or prevent obesity,” said Yu-Hua Tseng, Ph.D. an Assistant Investigator in the Joslin Section on Obesity and Hormone Action.

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