Prostate Cancer may
stall Tumor growth with Raloxifene Drug Treatment
March 21st, 2006
from Cedars-Sinai found that a drug called Raloxifene may help in the
treatment of men with prostate cancer. Raloxifene is a drug that is
currently on the market used to treat osteoporosis. The complete report
will be in the April 2006 issue of the British Journal of Urology
"We undertook this study because we
desperately need new therapies for patients with advanced prostate
cancer," said David B. Agus, M.D. who is the research director of the
Louis Warschaw Prostate Cancer Center at Cedars-Sinai and also is the
principal investigator of this study.
Prostate Cancer will kill
approximately 35,000 men this year and is the leading cause of cancer of
men in the United States. It is estimated that one in six men will be
diagnosed with prostate cancer some time in their lifetime.
already approved by the FDA and is in the market. It allowed
researchers to go directly to a clinical trial with this drug. The
participants of the trial were given a daily oral dose of Raloxifene.
They were monitored on a regular basis for any changes in the prostate
cancer. They say some participants that took Raolxifene had shown signs
that the prostate cancer tumor growth was stabilized by slowing and
stopping its spread.
"It used to be that to show
effectiveness through research studies, cancer drugs needed to shrink
tumors by 50 percent," Agus said. "Now, the new way of thinking about
the effectiveness of cancer drugs is whether they can slow cancer's
growth, which ultimately may significantly benefit patients."
There still would need to be further
randomized trials of Raloxifene to prove the effectiveness of treatment.
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