Botox Treatment – Cosmetic Procedure for
Wrinkle Removal could have Lower Doses, be Safer and more Effective
April 5th, 2006
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Botox Treatment |
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Scientists from
the Scripps Research Institute in La Jolla, California have found a way
to increase the potency of botulinum neurotoxin (Botox) which would be
safer and could last longer.
The new
combination of Botox could lead to lower price per dose because it would
be a lower dose. Lower doses of the botulinum neurotoxin could help to
avoid a complication that can occur with the immune system. The
scientists also say the new combination of botulinum neurotoxin cosmetic
treatment of wrinkles could last longer too.
Botulinum
neurotoxin is one of the most deadly poisons and considered a possible
bioterrorist weapon. However in the medical world, it has helped treat
migraine headaches, lazy eyes, and excessive sweating. People treated
for these other conditions had a side effect of wrinkles disappearing.
This happened because of the neurotoxin caused a paralyzing effects on
the muscles. That is when Botox came to be well known for the treatment
of wrinkles.
The lead author of
the study, Kim Janda, Ph.D., who is a chemistry professor at Scripps
along with his colleagues found a way to make a synthetic molecule that
causes the neurotoxin to be ‘superactivated’. The synthetic molecule
binds to specific proteins on the neurotoxin. This causes the toxin’s
paralyzing effects to be increased. That makes it more potent with less
of the toxin. The scientists estimate that the ‘superactivator’ makes
the toxin 14 times more potent than regular botulinum neurotoxin.
"We have developed
a synthetic molecule that binds to the toxin and increases its normal
function," Janda said. "The discovery of small molecule activators may
ultimately provide a valuable method for minimizing dosage, reducing
resistance, and increasing its clinical efficacy."
At this time the
scientist have not tested the ‘superactivated’ botulinum neurotoxin on
humans or animals and it would take at least 4 – 6 years for the proper
testing to be completed before it is available to consumers.
Nicole Wilson
Best Syndication
Books on Cosmetic Surgery
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