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Prostate Cancer Eating Cruciferous Vegetables can help slow Tumor Growth

April 5th, 2006

Prostate Cancer  Eating Cruciferous Vegetables can help slow Tumor Growth


Eating broccoli, cabbage, cauliflower and other cruciferous vegetables have shown to stop human prostate cancer cells from growing in mice.  The study is being presented today at the American Association for Cancer Research annual meeting in Washington, D.C.

"The contribution of diet and nutrition to cancer risk, prevention and treatment have been a major focus of research in recent years because certain nutrients in vegetables and dietary agents appear to protect the body against diseases such as cancer," said Shivendra Singh, Ph.D. who is the lead research and is also a professor of pharmacology and urology at the University of Pittsburgh School of Medicine. "From epidemiologic data, we know that increased consumption of vegetables reduces the risk for certain types of cancer, but now we are beginning to understand the mechanisms by which certain edible vegetables like broccoli help our bodies fight cancer and other diseases."


This study looked at phytochemicals that are found in cruciferous vegetables.  These phytochemicals are called isothiocyanates (ITCs).  The ITCs are made when these vegetables are cut or chewed.  The researchers found that it was this phenethyl-ITC (PEITC) the compound that caused the human prostate cancer cells from growing.  The amounts of the PEITC needed for a person to achieve this benefit could be accomplished with dietary intake of eating the cruciferous vegetables.

The researchers feed PEITC to mice who had grafted human prostate tumors.  They did this treatment daily for 31 days.  They also had a control group that had the tumor but was not fed PEITC.  The mice that did not have the PEITC had on average tumors that were 1.9 times more in volume.  The researchers also found that a protein called Bax also was present with the PEITC which also helped in the cancer cell death.


"Our next step is to design clinical trials to determine the efficacy of PEITC for prostate cancer prevention in men," said Dr. Singh.

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Nicole Wilson
Best Syndication

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Important:  The material on Best Syndication is for informational purposes only and is not a substitute for medical advice or treatment for any medical conditions. You should promptly seek professional medical care if you have any concern about your health, and you should always consult your physician before starting a fitness program.

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Copyright 2005 Best Syndication                   Last Updated Saturday, July 10, 2010 09:48 PM