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Diabetic Eye Health Statin Drugs May help Improve Blood Circulation possibly preventing Diabetic Retinopathy and Blindness

May 15th, 2006

Diabetic Eye Health  Statin Drugs May help Improve Blood Circulation possibly preventing Diabetic Retinopathy and Blindness


Researchers from Japan studied how simvastatin drug would effect blood circulation in the eye.  The study was first reported in the Archives of Ophthalmology.  While the results from this study are from healthy men, it potentially could lead to a new treatment for prevention of Diabetic Retinopathy which is caused by a lack of blood circulating in the eye and can eventually lead to blindness.

The researchers studied 12 healthy men ranging in age 19 through 23.  They gave half the participants a 20 milligram dose of simvastatin and the other half given a placebo over seven days.


Measurements for the intra-ocular pressure, blood velocity, blood flow, and plasma nitrite/nitrate data was measured in the eyes of all of the participants.  They measured the participants 90 minutes after they had taken the medication and followed up with another measurement 7 days later.

The results showed that the participants that were taking the simvastatin drug had a reduced intra-ocular pressure.  They also had a significant increase in blood velocity and blood flow.  There was also an increase in the amounts of plasma nitrite/nitrate.  The blood vessels did not change in size.


Future research would be needed with the simvastatin drug.  It is not known at this time if participants suffering from these types of eye diseases would benefit from statin drug treatment.

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Nicole Wilson
Best Syndication

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