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Enlarged Prostate – Botox may help relieve Symptoms of BPH

May 23rd, 2006

Enlarged Prostate – Botox may help relieve Symptoms of BPH

Botox Injection

Botox also known as botulinum toxin A may have a new treatment to help relieve the symptoms of benign prostatic hyperplasia (BPH) also known as enlarged prostate.  Botox which is known to be used in cosmetic procedures to remove wrinkles also helps in treating other conditions.  This new study using the toxin for enlarged prostate may add to Botox’s list of treatments. 

Researchers from the Chang Gung University Medical College, Taiwan and the University of Pittsburgh School of Medicine completed a study that injected Botox into the men that have an enlarged prostate gland.  They will present their results at the American Urological Association (AUA) and will be published in the AUA proceedings (abstract 1436).


Enlarged prostate is a very common disease that affects men as they get older.  There are over 50 percent of men over the age of 60 that suffer from an enlarged prostate. Men over the age of 80 are affected 80 percent of the time.  There are an estimated 40 to 50 percent of these men that will eventually have symptoms.  The symptoms include more frequent urination, urinary tract infections, and being able to completely empty the bladder.  The most severe symptom can cause damage to the bladder and kidneys.

"Millions of men in the United States suffer from enlarged prostate," said Michael B. Chancellor, M.D., professor of urology and gynecology at the University of Pittsburgh School of Medicine. "It's a challenging disease to live with because it causes frequent and difficult urination. Unfortunately, common treatments also are problematic because they carry some risk of serious side effects, such as impotence. Our results are encouraging because they indicate that Botox could represent a simple, safe and effective treatment for enlarged prostate."


There were 41 men that participated in this study that ranged in age from 49 to 79 years old.  They were symptomatic of BPH and did not benefit from standard medical treatment.  The men all received injections of Botox into their prostate glands.  The results were promising.  There were 31 patients out of the 41 that showed improvements.  The researchers report approximately a 30 percent improvement from urinary tract symptoms.  The improvements lasted up to one year after the injection for some of the patients.  Four out of five had the ability to empty their bladders completely within one week and up to one month after the injection occurred.

One reason that the Botox treatment works so well is that it causes the prostate gland to relax as it partially paralyzes tissue surrounding the injected area.  This eases up the pressure on the urethra. 


Dr. Chancellor also said that Botox reduces the size of the prostate gland through apoptosis which is programmed cell death.  This allows for the prostate to reduce in size.  By freeing up the pressure on the urethra it is possible to improve urine flow and reduce the amount of urine remaining in the bladder.  The patients did not report any significant side effects.

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Nicole Wilson
Best Syndication

Books on Enlarged Prostate

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Important:  The material on Best Syndication is for informational purposes only and is not a substitute for medical advice or treatment for any medical conditions. You should promptly seek professional medical care if you have any concern about your health, and you should always consult your physician before starting a fitness program.
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