Diabetes Type 2 – New
Understandings may help develop treatments in the Future
May 29th, 2006
Researchers have learned that SHP-1
protein plays a role in controlling blood glucose in Type 2 Diabetes
patients which could lead to new treatments in the future.
Professor André Marette (Laval
University) oversaw a group of researchers that included Nicole
Beauchemin (McGill University), Martin Oliver (McGill University Health
Centre) and Katherine Siminovitch (University of Toronto) who all
participated in a Canadian and American team. The results have
been published in
the May issue of Nature Medicine.
ShP-1 protein was already known to
play a role in the immune system. The researchers wanted to verify
how the protein worked in the regulation of metabolism.
Researchers were able to research the SHP-1 protein with a series of mutant
or genetically modified mice. These mice produced either very
little or had none of the SHP-1 protein.