Lung Cancer –
Tumor growth increases with loss of a Protein
May 31st, 2006
Zafira Castaño who
is a researcher and Doctor in Biochemistry from the University of
Navarra in Spain, discovered a connection between lower levels of αCP4
protein in early stages of lung cancer and may help make tumors grow.
that these αCP4 protein cells are found on tissue cells within a healthy
lung. However in a lung that was in first phase of cancer there was a
loss of this protein. The αCP4 protein was also lacking in 67% of the
tumors as well.
To confirm the
findings Castaño took samples of various cellular lines from different
kinds of lung tumors. She then introduced a series of the αCP4 protein
to the tumor tissues to see what would result. Some of the tumors
responded to the introduction of the protein. Tumor proliferations were
reduced with malignant tumors of large cells she noticed that their
ability to grow was reduced.