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Statin Drugs Recommended for those Undergoing Surgery to Fight Infections  - Prevent Sepsis

January 25th 2006

Statin Drugs Recommended for those Undergoing Surgery to Fight Infections  - Prevent Sepsis

Crestor various strengths

Statins may lower the risk of major infections, according to a study published in this weeks The Lancet.  Statins are a class of drugs that lower cholesterol.  Lipitor, Zocor, Pravachol, Lesocol, Crestor and Mevacor are all statin drugs. 

These statin drugs may have side effects including liver and kidney damage according to the newmediaexplorer.org website.  The Bayer statin Baycol was removed from the market because of these side effects.

There may be some good side effects as well.  Researchers analyzed 69,000 patients who were initially hospitalized for a heart problem.  They followed these patients and found that those who used statin drugs were much less likely to develop sepsis than those that did not use the drug.  Sepsis is a massive bloodstream infection.


These statin drug users were also less likely to develop a sever case of sepsis and die from it.  People that need to undergo high-risk surgeries may want to consider starting a short-term course of statins, according to ABC News.  Dr. Donald A Redelmeir of the Sunnybrook and Women’s College Health Sciences Center in Toronto said these patients should consider the drugs use “even if they do not have heart disease or high cholesterol."

Statins may benefit people at a high risk for developing infections.  People with diabetes, kidney failure and previous infections should consider using these drugs.  Also patients undergoing bowel resection surgery should consider statins to prevent a bacterial infection. 


Other cholesterol lowering drugs such as Cholestyramine and nicotinic acid did not have the same effect.  This study backs up previous animal studies that showed a reduced risk of sepsis when statins were used.  It is not clearly known why statins prevent infections, but they may do this by altering the immune system and blocking inflammation.

According to the Mercola.com website, there are at least 12 million Americans taking cholesterol-lowering drugs, mostly statins, and experts' recommend that another 23 million should be taking them. It is important to remain educated on this issue and understand statin drug side effects. 

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By Dan Wilson
Best Syndication Staff Writer

Books on Heart Disease

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Copyright 2005 Best Syndication                                            Last Updated Saturday, July 10, 2010 09:49 PM