Link Between Asthma
and Leptin Found
Lungs and Airway
Research from the Southern Illinois University School of Medicine in
Springfield suggests that there may be link between leptin and asthma.
Previous studies have determined that there was a link between leptin
levels and childhood asthma. This prompted researchers to determine if
the same was true for adults.
Doctor Akshay Sood and colleagues looked at data from the Third National
Health and Nutrition Examination Study, and found that there was a
correlation between leptin levels and asthma. Of the 5,876 participants
they found that the association was stronger in women than men, and
stronger in premenopausal women than in postmenopausal women.
Leptin is an inflammatory compound produced by body fat. Earlier
studies found that there was a relation between body mass index (BMI)
and asthma risk. BMI is a measure of weight in relation to height. The
researchers can not prove cause and effect, but they say that in animal
studies leptin plays a pro-inflammatory role in the airways.
It is believed that the mechanical effects of obesity seem to play a big
role in asthma, according to Reuters News service. Sood plans on
investigating the roles of other fat-produced compounds in the
development of asthma. They will also focus on adiponectin, an
anti-inflammatory protein that may counter the effects of leptin. Their
research will be published in the next issue of Thorax.
By Dan Wilson
Books on Heart Disease
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