Stress Hormones Cause
Depression - New Drugs May Target Cortisol to Prevent Chronic Anxious
Behavior and Mood Disorders
April 17th 2006
Researchers believe that long term exposure to stress causes depression.
Many medical professionals have suspected this, but lacked the evidence.
Neuroscientists at Harvard Medical School, and its affiliate Mclean
Hospital, have shown that long-term exposure to a stress hormone in mice
directly resulted in the anxiety that often comes with depression.
Researchers already knew that people with depression had high levels of
the human stress hormone, cortisol, but were not sure if it was a cause
or effect. They now believe that long-term exposure to cortisol
actually contributes to the symptoms of depression.
mice to both short term and long-term durations of the rodent stress
hormone, corticosterone. According to Paul Ardayfio, PhD candidate, and
Kwang-Soo Kim, PhD, chronic stress, such as caring for a spouse with
dementia, rather than acute stress, has been associated with