Cancer By Promoting Cell Death - Both Skin and Bowel Cancer Studies Show
Voluntary Workouts Reduce Risk
May 13th 2006
Two studies highlight the benefits of exercise, including lower risks of
skin cancer and bowel cancer. In the first study, published in the
journal Carcinogenesis, exposed female mice to ultraviolet B light (UVB).
The researchers found that the mice that had 24-hour access to running
wheels took longer to develop skin tumors and had fewer of them. The
tumors were also smaller in the mice that were exercising.
Scientists believe that programmed cell death, called apoptosis, can be
triggered by exercise. The problem with cancer cells is that they do
not die like normal cells. Dr. Allan Conney said “Preliminary
indications from follow-up work in the laboratory suggest that voluntary
exercise enhances UVB-induced apoptosis in the skin, and that it also
enhances apoptosis in UVB-induced tumors. So, although UVB is triggering
the development of tumors, exercise is counteracting the effect by
stimulating the death of the developing cancer cells.” Dr. Conney is
Garbe professor of Cancer and Leukemia Research.