Join Now!
Home  Top Stories  Sports  Entertainment  Health News  Business  Personal Finance 
Real Estate  Business Finance  Insurance  Consulting 
Tax News  Forum
 

Writers






 


Featured Articles







BUSINESS



 




How much should you be saving on Health Insurance?

Cooking-free  gourmet frozen meals

120 x 60 Firm Tummy


Search:

 

Health

 

Increased Heart Risk Associated With Ibuprofen Use - BMJ Study Shows Risk of Some NSAIDs Similar to Vioxx For Heart Attacks

June 1st 2006

Increased Heart Risk Associated With Ibuprofen Use - BMJ Study Shows Risk of Some NSAIDs Similar to Vioxx For Heart Attacks

Health

Researchers have evaluated several studies and have concluded that some non-steroidal anti-inflammatory drugs (NSAIDs) may pose a risk of cardiovascular events similar to Cox-2 Inhibitors like Vioxx. The study, published in the British Medical Journal (BMJ), combined all the available randomized data from 138 trials for form a conclusion.  This meta-analysis included 140,000 patients.

The researchers from Italy and the UK reviewed the data and found (as expected) a correlation between Cox-2 inhibitors and an increased risk of vascular events. There was not enough data to determine whether these risks were dose dependent, or whether the risks might differ among aspirin and non-aspirin users.

 

They did find that two of the NSAIDs studied had an increased risk of vascular events associated with them.  Both diclofenac and ibuprofen, were linked with a similar increase risk of vascular events, just like COX 2 inhibitors.  Interestingly the risk was lower for naproxen when used in high doses.

They compared COX 2 inhibitor with the placebo, and a COX 2 inhibitor with a traditional NSAID in randomized trials.  By combining the trails, they believe their analysis provides a much more reliable estimate of the cardiovascular risks of these drugs. 

 

The researchers say the average increased risk of vascular events was modest among the people studied in the trials: For every 1,000 people taking an NSAID or COX 2 inhibitor, around three extra people per year would have a vascular event, most likely a heart attack.

In conclusion, the researchers believe that very large randomized trials are needed to identify which anti-inflammatory drug regimens minimize serious cardiovascular and gastrointestinal problems.  Also, it is recommended that doctors work with their patients to choose the best solutions for treating their chronic pain.

 
 
Comment on this Article at our Forum

Submit your own Article

Pain and Arthritis Special Topic

Lung and Heart News

  RSS Feed to our Heart/Lung News

  RSS Feed to Pain / Arthritis News

  RSS Feed to our health News

  RSS Feed to all of our News

Add to Google Add to My AOL
Add to My Yahoo! Subscribe with Pluck RSS reader
Subscribe in NewsGator Online
Add this feed to Your C-Net
Subscribe in Bloglines Subscribe in Rojo

Dan Wilson
Best Syndication

Books about Pain

Keywords and misspellings:  pane reumatoid rhumatoid rhumatoidal rheumatoidal arthritis arthrites pain


Important:  The material on Best Syndication is for informational purposes only and is not a substitute for medical advice or treatment for any medical conditions. You should promptly seek professional medical care if you have any concern about your health, and you should always consult your physician before starting a fitness program.
Google
 
Web BestSyndication.com

About   Contact   Site Map

Copyright 2005 Best Syndication                   Last Updated Saturday, July 10, 2010 09:51 PM