Allergy More Likely In
Clean Environments - Duke Researchers Compared Lab Mice and Rats to Wild
Rodents - Good Hygiene Causes Allergies
June 20th 2006
Duke University researchers say countries that are “overly” hygienic
have a tendency to acquire autoimmune disease and allergic reactions.
Their research involved a comparison between wild mice and common rats
to laboratory mice and rats.
The researchers focused on the animal’s production of various
antibodies, known as immunoglobulins, either associated with autoimmune
disease or associated with allergy. When the mice, rats, or humans for
that matter, encounter an invader or antigen, their immune systems kick
into action producing antibodies that bind to the invader and destroy
According to William Parker, PhD, there are many classes of
immunoglobulins (Ig). Parker is an assistant professor of experimental
surgery and senior member of the study team.