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Flurizan Shows Benefits for Treating Alzheimer's Disease - Slows Onset of Confusion Depression and Aggression Over 24 Month Period

July 19th 2006

Flurizan Shows Benefits for Treating Alzheimer's Disease - Slows Onset of Confusion Depression and Aggression Over 24 Month Period

Flurizan Benefits

Researchers have demonstrated Flurizan can help patients with Alzheimer’s disease.  Flurizan, made by Myriad Genetics, when given in the larger doses (800 milligram twice a day) can slow the cognitive decline caused by Alzheimer ’s disease. 

In this study, the groups taking the higher doses demonstrated a substantial benefit over other dose groups in the study and that this benefit continued over 24 months.  The testing included memory loss, cognition and global function.

This is considered a small mid-state trial, but the results are promising.  Adrian Hobden, Ph.D., President of Myriad Pharmaceuticals, Inc. said "The 24 month data completes the Phase 2 follow-on trial with mounting evidence of efficacy against mild Alzheimer's disease that consistently increased over the course of the study.  The results are consistent with a mode of action for Flurizan that is modifying the course of the underlying disease process."


There was a significant increase of time before patients experienced problems.  Some problems experienced by Alzheimer’s patients include agitation, aggression, confusion and a state of depression. 

Dr. Jocobo Mintzer Said "The decrease in the number of psychiatric events and the dramatic lengthening in time before patients experienced such events while on Flurizan is an important feature for spouses and caregivers of Alzheimer's patients, as well as for the patients themselves."  Mintzer is Professor in the Departments of Psychiatry and Neurosciences and Director of the Alzheimer's Disease Program at the Medical University of South Carolina.


The doctor added “These events can be as troubling as the more widely recognized memory loss and decline in cognition to those involved in the devastating deterioration caused by Alzheimer's disease."

Mintzer presented the findings at the 10th International Conference on Alzheimer's Disease and Related Disorders, in Madrid, Spain.

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