Agitates Ovarian Cancer – Less Stress will Slow Tumor Growth in Mice
Study – Beta Blockers Help
July 24th 2006
study on mice has shown that stress can cause tumors to grow more
quickly, and the effect can be blocked by a medication commonly
prescribed for heart disease. Dr. Anil Sood said
"This study provides
a new understanding of how chronic stress and stress factors drive tumor
growth." Sood is an associate professor of gynecologic oncology and
cancer biology and director of ovarian cancer research.
When the researchers blocked the stress hormone receptors using the
heart disease drug propronolol (a beta-blocker) in the mice, they were
able to stop the negative effects of the stress on tumor growth. The
researchers chose beta blockers because the same hormone receptors,
called beta adrenergic receptors, are found in the heart and normally
work to maintain blood flow.
interested in this research when they noticed patients with ovarian
cancer reported high levels of stress in their lives. They say stress
increases the blood flow to tumors.