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Asthma Allergy Immune System Special Topic       RSS Allergy Asthma News Feed
 
 

HIV Avoids Drugs By Hiding in Gut - New Therapy Breakthrough Called HAART Suppresses Inflammation and Aids in Better Recovery

HIV Avoids Drugs By Hiding in Gut - New Therapy Breakthrough Called HAART Suppresses Inflammation and Aids in Better Recovery

Dandekar

New research shows that HIV is able to avoid the powerful antiretroviral therapy (ARV) drugs by hiding it the guts of AIDS patients.  This discovery may lead to reducing the virus’s presence in the blood, according to a report in the TimesOnline by Sam Lister. This may also explain why the virus continues to replicate and suppress the immune system even when blood samples show the drugs are working.

In the report, Professor Satya Dandekar said “The real battle between the virus and exposed individuals is happening in the gut immediately after viral infection. We need to be focusing our efforts on improving treatment of gut mucosa, where massive destruction of immune cells is occurring.”   Dandekar led the study and is head of the university’s department of medical microbiology and immunology at the University of California, Davis.  Complete Article


Indoor Swimming Pools Linked to Childhood Asthma - European Study Shows Increased Rate of Wheezing In Children From Western Countries

Indoor Swimming Pools Linked to Childhood Asthma - European Study Shows Increased Rate of Wheezing In Children From Western Countries

Swimming Pool

European researchers believe that there may be a relation between indoor swimming pools and childhood asthma.  The researchers compared countries in Europe with the number indoor swimming pools.  They found that countries with more indoor swimming pools had 2 to 3 percent increased number of asthma cases. 

The research involved almost 190,000 young teenagers (13 and 14 year olds) from 21 countries across Europe.  The number of indoor swimming pools varied by a factor of 20 between Eastern and Western Europe.  There was one indoor pool for every 50,000 inhabitants in Western Europe and one for every 300,000 inhabitants in Eastern Europe.  Complete Article


Overweight People More Likely To Have Asthma - Obesity Linked to Lung Ailment - Australian Study Found Protein That Triggers Attacks

Overweight People More Likely To Have Asthma - Obesity Linked to Lung Ailment - Australian Study Found Protein That Triggers Attacks

Inhaler

Australian researchers at Sydney's Garvan Institute believe there is a link between obesity and asthma and speculate that this is the reason why asthma is on the increase in Western countries.  They have found a fatty acid binding protein called aP2 in the lungs of asthma patients.

This protein has already been known for its role in diabetes and obesity.  Now they know it is present in the lungs where it is crucial in controlling inflammation in asthma.

There are various triggers, such as dust mites and pollen that bring on asthma attacks.  The scientists believe that high levels of aP2 in human lung cells trick the body into thinking it is undergoing an asthma attack.  The attack is characterized by inflammation of the airways, a tightening of the surrounding muscles, and excess mucus production.  Complete Article


Celiac Disease – Enzyme Therapy approach to treating Gluten Intolerance

Celiac Disease – Enzyme Therapy approach to treating Gluten Intolerance

Wheat Bread

Celiac Sprue which is an inherited inflammatory disorder of the small intestine may have a non-dietary therapy that may work.  Currently a celiac sufferer would not be able to eat gluten in their diet.  Gluten is found in wheat, barley, and rye.  The gluten cases an inflammatory reaction that can damage the small intestines.  It is estimated that there are approximately 1 in 200 people that suffer from celiac disease around the world.  Celiac Disease – Enzyme Therapy approach to treating Gluten Intolerance


Allergy More Likely In Clean Environments - Duke Researchers Compared Lab Mice and Rats to Wild Rodents - Good Hygiene Causes Allergies

Allergy More Likely In Clean Environments - Duke Researchers Compared Lab Mice and Rats to Wild Rodents - Good Hygiene Causes Allergies

Wild Rodents

Duke University researchers say countries that are “overly” hygienic have a tendency to acquire autoimmune disease and allergic reactions.  Their research involved a comparison between wild mice and common rats to laboratory mice and rats. 

The researchers focused on the animal’s production of various antibodies, known as immunoglobulins, either associated with autoimmune disease or associated with allergy.  When the mice, rats, or humans for that matter, encounter an invader or antigen, their immune systems kick into action producing antibodies that bind to the invader and destroy it. 

According to William Parker, PhD, there are many classes of immunoglobulins (Ig).  Parker is an assistant professor of experimental surgery and senior member of the study team. Allergy More Likely In Clean Environments - Duke Researchers Compared Lab Mice and Rats to Wild Rodents - Good Hygiene Causes Allergies


Common Asthma Inhalers Can Cause Death with Repeated Use – Formoterol Serevent and Advair Named In Study  

Common Asthma Inhalers Can Cause Death with Repeated Use – Formoterol Serevent and Advair Named In Study

Inhaler

Researchers from Stanford and Cornell Universities are recommending three asthma inhalers be pulled from the U.S. market. Four out of five U.S. asthma-related deaths per year may be caused by inhalers containing the drugs salmeterol or formoterol. 

The researchers base their conclusions on 19 published studies involving 33,826 patients.  There statistical analysis found that the patients who inhaled the long-acting beta-agonists salmeterol or formoterol  were 3.5 times more likely to die from asthma and 2.5 times more likely to be hospitalized.

Salmeterol is made by GlaxoSmithKline under the brand-names Serevent and Advair.  Foradil (brand name for Formoterol) is manufactured by Novartis Pharmaceuticals.  All three inhalers relieve asthma symptoms, but they also promote bronchial inflammation and sensitivity without warning.  The researchers admit the risk of death is relatively low, but 15 patients in the meta-analysis who were taking the beta-agonists died, compared with three in the placebo group, over a six-month period.  Common Asthma Inhalers Can Cause Death with Repeated Use – Formoterol Serevent and Advair Named In Study  

Asthma – Breathing Exercises can help in Mild Cases

Asthma – Breathing Exercises can help in Mild Cases

Exercise

A double blind randomized trial of different breathing exercises was tested to measure how it could help in the treatment of asthma.  The results were first published in the online edition of Thorax.

Researchers discovered that using a breathing exercise in mild asthma cases can reduce the need for using an inhaler by 80 percent and also reduced the dosage of medication needed.

There were a total of 57 adult participants that suffer from mild asthma and used the preventer inhaler at least four times a week were assigned randomly two separate breathing techniques.  The first breathing exercise was to use a shallow nasal breathing with slow exhalations.  The second breathing exercise used general upper body exercised along with relaxation.  Asthma – Breathing Exercises can help in Mild Cases


New Asthma Treatment - Fiber Optic Cable Fed Into Lungs - Bronchial Thermoplasty Therapy - Clinical Trials

New Asthma Treatment - Fiber Optic Cable Fed Into Lungs - Bronchial Thermoplasty Therapy - Clinical Trials

Alair Treatment

There is a new treatment for asthma sufferers called bronchial thermoplasty, where wires are snaked up inside the lungs to burn off some of the tissue that blocks the airways. This is a non-drug therapy, but is not without risk. The long term effects are not known, and it is possible that the procedure could cause wheezing.

The current therapy for asthma includes inhaling large doses of steroids twice a day.  According to John McKenzie of ABC news, that is not enough for some people.  He claims that this procedure could revolutionize the way those with asthma are treated.  New Asthma Treatment - Fiber Optic Cable Fed Into Lungs - Bronchial Thermoplasty Therapy - Clinical Trials


Antihistamine Causes Severe Breathing Problems in Children - Promethazine HCL Should Not Be Used On Children Under Two - FDA

Antihistamine Causes Severe Breathing Problems in Children - Promethazine HCL Should Not Be Used On Children Under Two - FDA

Promethazine HCL

The Food and Drug Administration (FDA) is warning parents and doctors that medications containing promethazine hydrochloride (HCl) should not be used to treat children under the age of two because of possible breathing problems.  The antihistamine can be found in tablets, syrups, injectables and even suppositories. 

There are reports of breathing problems and even some deaths associated with the drug involving children under the age of two.  The FDA says that parents and caregivers should also be careful and get a doctor’s advice about giving promethazine HCl in any form to children age two and older. 

According to an FDA press release, “the labeling on all products, brand name and generic, has been changed to reflect these strengthened warnings.”  The FDA is especially concerned and has alerted healthcare professionals, other caregivers, and patients that the drug is also found in cold and or cough syrups.  Antihistamine Causes Severe Breathing Problems in Children - Promethazine HCL Should Not Be Used On Children Under Two - FDA


Asthma – Dirty House is better than a clean one for preventing Asthma in Children

Asthma – Dirty House is better than a clean one for preventing Asthma in Children

Girl with Asthma Inhaler

A study published in the April 18th, online Journal of Allergy and Clinical Immunology showed that children that were exposed to more dust and microbials had less of a chance of developing asthma.

Researchers from Utrecht University in the Netherlands and Massey University in Wellington, New Zealand measured how much children were exposed to microbials when they were 3 months old and followed up and measured again at 4 years old.

The children were watched for the development of asthma symptoms such as wheezing or atopic sensitization.  Atopic sensitization can develop into allergies and may be inherited from one of their parents; if a child develops this allergy the reaction is instant when coming into contact with the allergen. Asthma – Dirty House is better than a clean one for preventing Asthma in Children


Telithromycin Effective Treatment for Asthma - Study Found Antibiotic Can Be Used To Treat Acute Asthma Attacks and Symptoms

Telithromycin Effective Treatment for Asthma - Study Found Antibiotic Can Be Used To Treat Acute Asthma Attacks and Symptoms

Asthma Treatment

London researchers say that the antibiotic, telithromycin, can hasten the recovery time of patients who have had asthma attacks by three days, as will reduce symptoms and improving lung function.  The study, published in the New England Journal of Medicine, demonstrated that this antibiotic can be used effectively to treat acute asthma attacks.

The antibiotic is not currently used for treating asthma.  Telithromycin is made by the world’s third largest pharmaceutical company, sanofi-aventis.  The study, part of the TELICAST (TELIthromycin, Chlamydophila and ASThma) study, investigated 278 patients at 70 centers around the world.

This was a randomized double blind study.  Within 24 hours of an acute asthma attack, patients were given either a single 800mg dose of telithromycin daily, or a placebo, in addition to their usual treatment.  Telithromycin Effective Treatment for Asthma - Study Found Antibiotic Can Be Used To Treat Acute Asthma Attacks and Symptoms


Link Between Asthma and Leptin Found

Link Between Asthma and Leptin Found

Lungs and Airway

Research from the Southern Illinois University School of Medicine in Springfield suggests that there may be link between leptin and asthma.  Previous studies have determined that there was a link between leptin levels and childhood asthma.  This prompted researchers to determine if the same was true for adults.

Doctor Akshay Sood and colleagues looked at data from the Third National Health and Nutrition Examination Study, and found that there was a correlation between leptin levels and asthma.  Of the 5,876 participants they found that the association was stronger in women than men, and stronger in premenopausal women than in postmenopausal women.  Link Between Asthma and Leptin Found


Early Antibiotic Use May be Linked to Asthma - Ear Infections Bronchitis and Upper Respiratory Infection Treatments May Lead to Childhood Asthma

Early Antibiotic Use May be Linked to Asthma - Ear Infections Bronchitis and Upper Respiratory Infection Treatments May Lead to Childhood Asthma

Asthma Patient X-ray

Researchers warn that antibiotic use may double the risk of childhood asthma.  According to a study by the University of British Columbia, “children under age 1 who are treated with an antibiotic are twice as likely to develop asthma in childhood.”

Current guidelines recommend antibiotics for children under the age of 2 who contract ear infections.  The study’s coauthor, Fawziah Marra, M.D, said “In children, antibiotics are commonly used to treat ear infections, upper respiratory tract infections, and bronchitis, but not every childhood infection requires an antibiotic.”  Since most upper respiratory tract infections and bronchitis are viral, antibiotics are ineffective.

Previous studies involving several hundred to several thousand youngsters have suggested a link between antibiotic use and asthma.  These earlier studies have been criticized for being too small, for relying on imprecise records on past antibiotic use.  This new analysis combines studies to create a larger pool for extrapolating the data.  Early Antibiotic Use May be Linked to Asthma - Ear Infections Bronchitis and Upper Respiratory Infection Treatments May Lead to Childhood Asthma


Cats Increase Risk For Eczema While Dogs Lower Chance - Babies and Children Exposed To Felines May Develop Atopic Dermatitis

Cats Increase Risk For Eczema While Dogs Lower Chance - Babies and Children Exposed To Felines May Develop Atopic Dermatitis

Health

Researchers from the University of Arizona say that children exposed to cats soon after birth have an increased risk of developing eczema.  Dogs on the other hand, had a protective effect.  According to Eczema.net, eczema is a general term encompassing various inflamed skin conditions. One of the most common forms of eczema is atopic dermatitis.  The condition is sometime called "atopic eczema".

The study which was presented at the American Thoracic Society International Conference on May 21st, involved 486 children who were followed since birth.  The researchers asked the parents how many dogs and cats were in the house at the time of birth.  They then came back a year later to determine which children developed eczema. 

They found that of the 134 children with cats in the house, 27.6 percent developed eczema.  Of the 286 children without cats, only 17.8 percent developed eczema. Cats Increase Risk For Eczema While Dogs Lower Chance - Babies and Children Exposed To Felines May Develop Atopic Dermatitis


Asthma – Dirty House is better than a clean one for preventing Asthma in Children

Asthma – Dirty House is better than a clean one for preventing Asthma in Children

Girl with Asthma Inhaler

A study published in the April 18th, online Journal of Allergy and Clinical Immunology showed that children that were exposed to more dust and microbials had less of a chance of developing asthma.

Researchers from Utrecht University in the Netherlands and Massey University in Wellington, New Zealand measured how much children were exposed to microbials when they were 3 months old and followed up and measured again at 4 years old.

The children were watched for the development of asthma symptoms such as wheezing or atopic sensitization.  Atopic sensitization can develop into allergies and may be inherited from one of their parents; if a child develops this allergy the reaction is instant when coming into contact with the allergen. Asthma – Dirty House is better than a clean one for preventing Asthma in Children


Gene Found for Eczema - May Lead to Therapies for Cause of Dry Skin - Not just Treatments for Symptoms

Gene Found for Eczema - May Lead to Therapies for Cause of Dry Skin - Not just Treatments for Symptoms

Eczema

Up until now, eczema therapies involved treating the symptoms.  This may change soon due to research led by the University of Dundee in Scotland, where they have discovered the gene which causes dry, scaly skin.  The dry skin can lead to eczema and asthma, according to researchers. 

The gene produces a protein called filaggrin which helps keep the skin protected by forming an outer barrier.  It is hoped that this finding will lead to a therapy of the underlying condition that causes dry skin and eczema.  Most current therapies involve ointments to treat dry skin and anti-inflammatory drugs to treat eczema. 

The filaggrin protein is usually found in the outermost layers of skin.  In people that are not affected by dry skin, this protein is abundant.  The protein also helps form a skin barrier keeping the water in, but in absence allows the skin to dry out. When the skin dries out, it may begin to flake off as well.  Gene Found for Eczema - May Lead to Therapies for Cause of Dry Skin - Not just Treatments for Symptoms 


Milk May Trigger Eczema Flare Ups

Milk May Trigger Eczema Flare Ups

Eczema

Most North Americans grew up being told that milk builds healthy bones and teeth, but scientists have questioned the validity of this dictum for years. There is evidence that milk not only fails to live up to this promise, but it can even cause a host of medical conditions, including eczema.

In fact, eliminating milk and dairy from your diet, along with the use of a topical eczema treatment to alleviate the dry, itchy condition of the skin, is often just what the doctor orders. Although most of the studies have been done on children, from 1988 to 1993, over 1500 articles were published about milk in medical journals.

Dr. Robert M. Kradjian of the Johns Hopkins School of Medicine culled these articles to omit inconclusive and irrelevant subjects and did a thorough study of the 500 articles remaining. Not one article referenced milk as the excellent food we have been led to believe. Milk May Trigger Eczema Flare Ups


 

 
 
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Copyright 2005 Best Syndication                                            Last Updated Sunday, July 11, 2010 01:18 AM