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Cure For Diabetes? American Diabetes Association Hopeful New Research Will Lead to End of Insulin Injections

Cure For Diabetes? American Diabetes Association Hopeful New Research Will Lead to End of Insulin Injections

A Cure?

Experts at the American Diabetes Association meeting say that early symptoms of diabetes and heart disease should be aggressively treated.  Half of all Americans will become insulin resistant, placing them at risk for diabetes. 

The American Diabetes Association says that researchers are working on a cure.  They say that cells transplanted six months ago from pigs into diabetic monkeys are alive and producing insulin. This is without the need for immune-suppressing drugs. 

So far the research has been done on rhesus monkeys.  They injected the monkeys, whose own pancreatic islets were destroyed, with encapsulate cells taken from pigs.  The good news is that the monkey’s immune systems did not recognize the substance as foreign and did not try to reject it.  Complete Article


Vegan Diet Best For Diabetes Patients - Diabetics Benefit More From Vegetarian Low Fat Foods 

Vegan Diet Best For Diabetes Patients - Diabetics Benefit More From Vegetarian Low Fat Foods

Vegees Best

Contrary to what the Atkins Diet would recommend, new research shows that people with type 2 diabetes do best with a low-fat vegetarian diet.  Originally Atkins designed his diet to help people with diabetes, but later noticed all of his patients also lost weight.

This new research in the journal Diabetes Care says that people with diabetes should avoid animal products such as meat and dairy.  They also say the vegan diet is superior to the diet recommended by the American Diabetes Association, WebMD reports.

Doctor Neal D. Barnard said "The diet appears remarkably effective, and all the side effects are good ones - especially weight loss and lower cholesterol.”  Barnard is chief researcher and adjunct professor of medicine at George Washington University and president of Physicians Committee for Responsible Medicine.  Complete Article


A Practical Approach To Healthy Eating – Control Blood Sugar with Diet – Manage Pre-Diabetes with Good Meals

A Practical Approach To Healthy Eating – Control Blood Sugar with Diet – Manage Pre-Diabetes with Good Meals

Health

You will never be healthy, eating healthy foods occasionally. You have to make healthy eating a habit if you want to obtain nutritional health.

I have been doing push-ups five days a week for over 25 years. My arms are pretty strong but it did not happen overnight. I did not do push-ups for a couple weeks or months and then stopped. I had to make push-ups a habit if I wanted to continuously get the results I have. Exactly the same holds true with having a healthy diet.

People jump on the "band wagon" of healthy eating when they read books or view web sites that talk about nutrition. While many of these books and web sites tell you what you should eat in-order to be healthy, they fail to teach you how to make healthy eating a habit. Thus in a short period of time when temptations come, people fall right back into their unhealthy eating habits.  Complete Article


Alzheimer’s Treatment - Diabetes Drug may help treat Alzheimer’s disease

Alzheimer’s Treatment - Diabetes Drug may help treat Alzheimer’s disease

Health

Research from the University of Virginia Health System and Case Western Reserve University found that a drug called piogliatozone HCI, which is used to treat type 2 Diabetes may also help people suffering with Alzheimer’s disease.  Alzheimer’s disease damages the brain’s ability to think and remember well and affects approximately 4.5 million people in the United States.

"We believe that the drug may reduce the body's inflammatory reaction to one of the toxic components that builds up in Alzheimer's, called amyloid plaque,” said Dr. David Geldmacher, an associate professor of neurology at UVa.  The study was first reported at the world's largest Alzheimer's conference, ICAD 2006, in Madrid, Spain on July 16th, 2006.  There is a growing idea of a relationship between diabetes and Alzheimer’s that have made ICAD organizers highlight this study.  Complete Article


Positive Link Between Glaucoma and Type 2 Diabetes - Most Common Form of Both Diseases are Related According to Study

Positive Link Between Glaucoma and Type 2 Diabetes - Most Common Form of Both Diseases are Related According to Study

Eye screening

New research has discovered a link between the most common type of glaucoma and type 2 diabetes.  Primary Open Angle Glaucoma (POAG), the most common form of glaucoma, is “positively associated” with the most common form of diabetes. 

Dr. Louis Pasquale, M.D. says “The study supports the notion that type 2 diabetes is associated with an increased risk of glaucoma.  While obesity fuels the type 2 diabetes epidemic, it appears that factors unrelated to obesity contribute to the positive association between type 2 diabetes and glaucoma. We were surprised to find this. Our study had a large enough sample to allow us to focus on type-2 diabetes only and to study its relation to newly diagnosed POAG cases. We were also able to correct for other factors that could contribute to glaucoma. Our work suggests, but in now way proves, that factors other than lifestyle behavior contributing to insulin resistance could lead to elevated intraocular pressure and glaucoma."  Pasquale is lead author of the study and co-director of the Glaucoma Service at the Massachusetts Eye and Ear Infirmary (MEEI) and an Assistant Professor of Ophthalmology at Harvard Medical School.  Complete Article


Coffee Reduces Risk of Diabetes - Decaffeinated Form Cuts Chance of Type-2 By 33 Percent

Coffee Reduces Risk of Diabetes - Decaffeinated Form Cuts Chance of Type-2 By 33 Percent

6 Cups of Coffee Better

Researchers from the University Of Minnesota School Of Public Health say that drinking coffee may reduce the risk of developing type-2 diabetes by up to 33 percent compared to women who don’t drink coffee.  The researchers used 28,812 postmenopausal women who did not have type-2 diabetes or cardiovascular disease as part of the Iowa Women's Health Study (1986-1997) to evaluate the risk.

Over the 11 year period, 1,418 women reported being diagnosed with the disease. The researchers then looked at the coffee intake.  Of the 28,812 women, about half (14,224) drank one to three cups of coffee per day; 2,875 drank more than six cups; 5,554 four to five cups; 3,231 less than one cup; and 2,928 none.  Coffee Reduces Risk of Diabetes - Decaffeinated Form Cuts Chance of Type-2 By 33 Percent


Fountain of Youth – Secrets to Living Longer new Understandings

Fountain of Youth – Secrets to Living Longer new Understandings

Fountain of Youth
1546 painting by Lucas Cranach

Have you ever wondered why some people live to be 100 years old and still are able to live independently?  Researchers have found some possible clues that may help to understand the differences in our bodies as we age.  Studies that give clues to how to live longer are being presented at the International Congress of Neuroendocrinology in Pittsburgh, PA from June 19-22.

One study showed that increase growth hormone may improve the quality of life in elderly and allow them to remain independent for a longer time.  The study conducted by George R. Merriam, M.D. who is the professor of medicine at the University of Washington / VA Puget Sound Health Care System along with colleagues completed a study of oral medication of growth hormones with elderly participants.  Fountain of Youth – Secrets to Living Longer new Understandings


Type 2 Diabetes – Elevated levels of RBP4 early indication of Insulin Resistance

Type 2 Diabetes – Elevated levels of RBP4 early indication of Insulin Resistance

Exercise can help lower RBP4 levels

A recent study found that increased levels of retinol binding protein 4 (RBP4) molecule helps predict the early stage of insulin resistance which is the one of the major reasons why most people develop type 2 diabetes and cardiovascular disease.  This study led by researchers from Beth Israel Deaconess Medical Center (BIDMC) was first reported in the June 15th issue of The New England Journal of Medicine (NEJM).

It may become possible to develop anti-diabetic therapies that lower RBP4 levels.  By measuring for elevated levels of RBP4, this could be used as a diagnostic tool to assess people’s risk for developing diabetes before the disease becomes onset.  Type 2 Diabetes – Elevated levels of RBP4 early indication of Insulin Resistance


Compare Januvia and Galvus Diabetes Drugs - Both Lower Blood Sugar with Fewer Side Effects than Glipzide Glucotrol - Weight Loss Too

Compare Januvia and Galvus Diabetes Drugs - Both Lower Blood Sugar with Fewer Side Effects than Glipzide Glucotrol - Weight Loss Too

Glucose Monitor

Two pills from competing pharmaceuticals have shown promise in trials as an effective treatment for type-2 diabetes, but without the side effects.  Other drugs on the market can cause low blood sugar and weight gain side-effects, so these new drugs may be better. 

It is hoped the drugs will reach the US market in less than a year.  Forbes has reported that the combined sales could reach $5 billion by 2010.  The drugs, Januvia and Galvus (made by Merck and Novartis respectively), spare the side effects while preserving the beta cells in the pancreas.  These cells produce insulin which helps reduce glucose in the blood.  They usually die off in diabetes patients.  Compare Januvia and Galvus Diabetes Drugs - Both Lower Blood Sugar with Fewer Side Effects than Glipzide Glucotrol - Weight Loss Too


Pfizer Says New Insulin Inhaler Available Next Month - Inhaled Diabetes Drug Exubera Will Cost More But Patients Gain Less Weight

Pfizer Says New Insulin Inhaler Available Next Month - Inhaled Diabetes Drug Exubera Will Cost More But Patients Gain Less Weight

Exubera

In January the Food and Drug Administration (FDA) approved Exubera, an inhaled insulin drug.  Now the drug maker, Pfizer Inc, says they hope to launch Exubera in the United States next month. 

Pfizer, the world’s largest drug maker, expects to market the product for adults with either Type 1 or Type 2 diabetes.  Sales are expected to top $1 billion a year. 

The drug appears safe, according to Reuters.  In trials, it has been able to safely control blood sugar over a two-year period.  It is expected than many Americans will switch to this new method of introducing insulin into their body. 

There are no insulin pills because the compound is destroyed by stomach acid.  This is the reason diabetics have had to rely on injecting themselves with insulin daily.  Exubera will cost more than the current injectable type.  It may cost double or triple the current injectable insulin.  Pfizer Says New Insulin Inhaler Available Next Month - Inhaled Diabetes Drug Exubera Will Cost More But Patients Gain Less Weight


Type 2 Diabetes – PSARL Gene discovered that may lead to a Cure

Type 2 Diabetes – PSARL Gene discovered that may lead to a Cure

Eating Healthy Foods

According to an Australian newspaper The Herald Sun, a group of Victorian scientists discovered the gene that is responsible that contributes to the development of Type 2 Diabetes.

Type 2 diabetes is not just an epidemic in the United States.  Australia is greatly impacted with 100,000 newly diagnosed patients each year.  The reason for the dramatic increase of type 2 diabetes is due to the dietary choices and lack of exercise.

ChemGenex Pharmaceuticals scientists from Geelong would want to develop a DNA diagnostic test that would be on the Australian market in 2 years.  They could test the DNA by taking a swab to the inside of the patient’s mouth.  Type 2 Diabetes – PSARL Gene discovered that may lead to a Cure


Harvard Begins Human Embryonic Stem Cell Research - University Will Use Private Funds to Bypass Funding Ban on Cloning - Diabetes Leukemia

Harvard Begins Human Embryonic Stem Cell Research - University Will Use Private Funds to Bypass Funding Ban on Cloning

Daley - Melton - Eggan

Researchers from Harvard University have begun experiments using Somatic Cell Nuclear Transfer (SCNT) to create disease-specific stem cell lines.  It is hoped this research will be useful in developing treatments for a wide range of now-incurable conditions afflicting tens of millions of people.

The school believes this is the first noncommercial effort in the United States to use human embryonic stem cells in a series of experiments whose principle has already been proven in animals.  It is hoped that the research will lead to treatments or cures for blood diseases like leukemia and possibly diabetes.  Harvard Begins Human Embryonic Stem Cell Research - University Will Use Private Funds to Bypass Funding Ban on Cloning - Diabetes Leukemia


Type 1 Diabetes – Gene Therapy prevented Onset of Diabetic Symptoms in Mice Study

Type 1 Diabetes – Gene Therapy prevented Onset of Diabetic Symptoms in Mice Study

Mouse

Researchers from the University of Pittsburgh, Pennsylvania were successful at preventing mice from developing the onset of hyperglycemia.  The method for the prevention was by introducing a gene encoding for cytokine.  Cytokine is a protein that arouses and hinders the production and/or job of the immune cells from making insulin producing cells.  The research was first presented at the American Society of Gene Therapy Annual Meeting in Baltimore which was May 31st through June 4th.

There is currently an estimated 700,000 people in the United States that have Type 1 diabetes.  Type 1 diabetes is caused because of an autoimmune disorder. The body attacks the insulin producing cells found in the pancreas.  Not only is do type 1 diabetes individuals have chronic hyperglycemia complications include blindness, kidney failure, heart disease, and nerve damage.  Another name for type 1 diabetes is juvenile diabetes.  The disorder usually begins in children however adults also can develop this condition later in life as well.  Type 1 Diabetes – Gene Therapy prevented Onset of Diabetic Symptoms in Mice Study


Diabetic Nerve Health – Success with a Trial for treatment of Neuropathy associated with Diabetes

Diabetic Nerve Health – Success with a Trial for treatment of Neuropathy associated with Diabetes

Professor David Tomlinson

Testing for a potentially new treatment for nerve damage caused by diabetes has shown some success with preclinical and early patient trials in the United States.

Researchers from The University of Manchester,UK discovered a way to inject a therapy into diabetic patients which help to stimulate genes.  By doing this therapy it may be possible to prevent nerve damage in the hands and feet of diabetic patients.

This treatment could help prevent foot amputations of thousands of diabetics each year. The World Health Organization has estimated there would be 300 million people worldwide that could have diabetes by 2025.  Diabetes is being diagnosed in young to middle age adults and would put them at a higher risk for amputations because of the long-term complications of this disorder.  Diabetic Nerve Health – Success with a Trial for treatment of Neuropathy associated with Diabetes


Diabetes Type 2 – New Understandings may help develop treatments in the Future

Diabetes Type 2 – New Understandings may help develop treatments in the Future

Mice

Researchers have learned that SHP-1 protein plays a role in controlling blood glucose in Type 2 Diabetes patients which could lead to new treatments in the future. 

Professor André Marette (Laval University) oversaw a group of researchers that included Nicole Beauchemin (McGill University), Martin Oliver (McGill University Health Centre) and Katherine Siminovitch (University of Toronto) who all was part of a Canadian and American team.  The results will be published in the May issue of Nature Medicine.  Diabetes Type 2 – New Understandings may help develop treatments in the Future


One Third of Diabetes Cases Are Undiagnosed 

One Third of Diabetes Cases Are Undiagnosed

Walk 5 days week

The National Institute of Health (NIH) reported that one third of those with diabetes do not realize they have it.  Although the percentage of adults with undiagnosed diabetes has not changed over the years, about 2.8 percent of all US adults have diabetes and don’t know it.

Both the NIH and the Centers for Disease Control and Prevention (CDC) analyzed national survey data from two periods — 1988 to 1994 and 1999 to 2002.  They say the number of adults over the age of 20 with diabetes has risen from 5.1 percent to 6.5 percent.

The study published in the June 2006 issue of Diabetes Care, says that type 2 diabetes accounts for up to 95 percent of all diabetes cases and virtually all undiagnosed diabetes cases.  People with the disease have high levels of blood glucose resulting from defects in insulin production, insulin action, or both.  One Third of Diabetes Cases Are Undiagnosed 


Metabolic Syndrome – Increased risk for Heart Failure in Middle Age

Metabolic Syndrome – Increased risk for Heart Failure in Middle Age

Pritikin Diet

Metabolic syndrome is a condition which consists of a group of symptoms.  The symptoms includes abdominal obesity, high blood pressure, high triglyceride levels along with low HDL (“good”) and high LDL (“bad”) cholesterol levels and diabetes.  Third National Health and Nutrition Examination Survey said that there are approximately 24 percent of adults in the United States over the age of 20 that have the metabolic syndrome.  Approximately 40 percent of the people over the age of 60 have the metabolic syndrome.  There are about 47 million people in the United States that have metabolic syndrome.

A report in Heart Online First said that people with metabolic syndrome have a significant increased risk for developing heart failure in their middle age years.  Metabolic Syndrome – Increased risk for Heart Failure in Middle Age


Diabetic Eye Health – Statin Drugs May help Improve Blood Circulation possibly preventing Diabetic Retinopathy and Blindness

Diabetic Eye Health – Statin Drugs May help Improve Blood Circulation possibly preventing Diabetic Retinopathy and Blindness

Eye

Researchers from Japan studied how simvastatin drug would effect blood circulation in the eye.  The study was first reported in the Archives of Ophthalmology.  While the results from this study are from healthy men, it potentially could lead to a new treatment for prevention of Diabetic Retinopathy which is caused by a lack of blood circulating in the eye and can eventually lead to blindness.

The researchers studied 12 healthy men ranging in age 19 through 23.  They gave half the participants a 20 milligram dose of simvastatin and the other half given a placebo over seven days.  Diabetic Eye Health – Statin Drugs May help Improve Blood Circulation possibly preventing Diabetic Retinopathy and Blindness


Stroke Prevention - Recommendations by the American Stroke Association to lower the Risk of having a Stroke

050506-stroke_prevention_american_stroke_association_recommends_steps_to_lower_stroke_risk.jpg

AlsoSalt salt substitute

Preventative treatments to avoid a stroke have been recommended by the American Stroke Association.  The report of guideline recommendations were published in the rapid access issue of Stroke: Journal of the American Heart Association.

"Stroke remains a major public health problem. Its human and economic toll is staggering," said Larry B. Goldstein, M.D. who is lead author of the report and chair of the association's Stroke Council.  Stroke Prevention - Recommendations by the American Stroke Association to lower the Risk of having a Stroke


Diabetes Type 1 – Potential Cure for Insulin Dependent Juvenile Diabetes

Diabetes Type 1 – Potential Cure for Insulin Dependent Juvenile Diabetes

One Touch Blood Glucose monitor

A team of researchers from the La Jolla Institute for Allergy and Immunology (LIAI) have made a major discovery that could lead to a potential cure for type 1 diabetes.  The research team was led by Matthias von Herrath, M.D., an internationally recognized expert on the molecular basis of type 1 diabetes has plans for human clinical trials to begin later in the year.

The treatment in this study used a combination to reverse the recent onset of type 1 diabetes in the majority of lab animals that they tested.  Type 1 diabetes is caused by an immune system that attacks the pancreas which causes a deficiency of insulin production.  Type 2 diabetes is usually caused by being obese or overweight.  The report was first published in the Journal of Clinical Investigation.  Diabetes Type 1 – Potential Cure for Insulin Dependent Juvenile Diabetes


Alzheimer’s disease – Risk Increases in Overweight and Obese People in their 40’s

Alzheimer’s disease – Risk Increases in Overweight and Obese People in their 40’s

Lafayette Skinfold Caliper

Researchers found that people that are either overweight or obese in their 40’s have a greater risk of developing Alzheimer’s disease later in life.  The research was first presented at the American Academy of Neurology 58th Annual Meeting in San Diego, California that was held the beginning of this month.

This large scale study followed 9,000 people for a period of 30 years.  The study measured skin fold thickness of the back of the upper arm and also under the shoulder on the back.

The people that had the higher skinfold measurements in their 40’s had a higher chance for developing Alzheimer’s disease compared to those that had the smallest measurements.  The people that had the highest skinfold measurement of the back were three times more likely to develop Alzheimer’s compared to those who had the smallest measurement of the back.  The people that had the largest skinfold measurement of the arm were 2 ½ times more likely to have Alzheimer’s disease later on compared to those that had the smallest arm skin fold measurement.  Alzheimer’s disease – Risk Increases in Overweight and Obese People in their 40’s


Shock Wave Blasting Treatment of Kidney Stones Increases Risk of Diabetes and High Blood Pressure (Hypertension) - Lithotripsy

Shock Wave Blasting Treatment of Kidney Stones Increases Risk of Diabetes and High Blood Pressure (Hypertension) - Lithotripsy

Kidney and Bladder

The use of shock waves to break up impassable kidney stones significantly increased the risk for diabetes and hypertension later in life.  Mayo Clinic researchers conducted a study concerning this common treatment that emits shockwaves to break the kidney stone into smaller “sandlike” pieces which are able to pass spontaneously with the urine, usually within a month. 

According to Amy Krambeck, MD, “This is a completely new finding. This opens the eyes of the world of urology to the fact that hypertension and diabetes are potential side effects. We can't say with 100 percent certainty that the shock wave treatment for the kidney stones caused diabetes and hypertension, but the association was very strong. The risk of developing diabetes after shock wave lithotripsy is almost four times the risk of people with kidney stones treated with medicine, and the risk of developing hypertension is one and one-half times, which is a significant risk increase."  Amy is a clinical urology resident at the Mayo Clinic and lead author of the study. Shock Wave Blasting Treatment of Kidney Stones Increases Risk of Diabetes and High Blood Pressure (Hypertension) - Lithotripsy


Metabolic Syndrome could be prevented by Eating a Diet Rich with Magnesium

Metabolic Syndrome could be prevented by Eating a Diet Rich with Magnesium

Soybeans

A 15 year study found that people that ate the most magnesium in their diets had a 31 percent less of a chance for developing metabolic syndrome. 

Metabolic syndrome is a group of conditions that include high blood pressure, high triglycerides, and low levels of “good” HDL cholesterol.  The metabolic syndrome people usually have an excessive amount of weight around their waist.  They struggle with blood sugar levels and can often develop type 2 diabetes.  They are also at an increased risk for developing heart disease.  Metabolic Syndrome could be prevented by Eating a Diet Rich with Magnesium


Diabetes Type 2 – Sleep Duration can increase risk for developing Adult Diabetes – Is Sleep Apnea the Culprit?

Diabetes Type 2 – Sleep Duration can increase risk for developing Adult Diabetes – Is Sleep Apnea the Culprit?

ResMed CPAP machine

A recent study of 1,709 men from ages 40 – 70 years of age were found that those that were not getting enough sleep or were getting to much sleep had an increased risk for developing Type 2 Diabetes.  The optimal sleep was found to be between 6 – 8 hours of sleep each night.

The study was a joint effort between researchers from the New England Research Institutes and the Yale School of Medicine.  The results were first published in the March issue of Diabetes Care.

The 1,709 men were participants in a 15 year research project called the Massachusetts Male Aging Study.  Researchers made house calls, had survey questionnaires and took blood samples over the 15 years of the study.  Diabetes Type 2 – Sleep Duration can increase risk for developing Adult Diabetes – Is Sleep Apnea the Culprit?


Heart Patients taking Crestor Statin Prescription Drug removed Plaque Build-up in their Arteries

Heart Patients taking Crestor Statin Prescription Drug removed Plaque Build-up in their Arteries

Crestor manufactured by AstraZeneca

This has been a landmark trial for the use of a cholesterol drug to reverse the buildup of plaque in coronary artery disease patients.

The Anglo-Swedish pharmaceutical company, AstraZeneca, reported this past Monday that their cholesterol drug, Crestor, has shown to reverse the atherosclerosis in a major clinical study.

The study was conducted over a two year period with 349 patients taking 40 milligrams of Crestor, a statin drug, once each day.  There were two-thirds of these patients that had shown regression of heart artery plaque build up when they were taking the maximum dose of Crestor.  Heart Patients taking Crestor Statin Prescription Drug removed Plaque Build-up in their Arteries


Obesity Risk – Fat causes Killer Inflammation Response in the Obese and Overweight

Obesity Risk – Fat causes Killer Inflammation Response in the Obese and Overweight

Fat Cells

Multiple research studies are coming to the same conclusion that excess body fat causes an inflammation response in their body that can be deadly.

A recent report in the International Journal of Obesity by researchers from the University of Warwick Medical School found that the biggest health risk to overweight and obese people is the killer inflammation response created from the excess body fat.

Professor F.P. Cappuccio and Dr. M.A. Miller looked at 3 different ethnic groups that were overweight or obese.  They measured the Body Mass Index (BMI) and the participant’s Waist-Hip Ratio (WHR) to determine the amount of body fat a person was carrying.  Obesity Risk – Fat causes Killer Inflammation Response in the Obese and Overweight


Diabetic Monkey cured with Pig Cells – Possible cure for Diabetes type 1

Diabetic Monkey’s cured with Pig Cells – Possible cure for Diabetes type 1

Insulin Injection

Researchers from the University of Minnesota’s Diabetes Institute for Immunology and Transplantation were successful at curing diabetes in monkeys using islet cells from pigs.  First reported online in the February 19th issue of Nature Medicine the researchers hope to begin human trials in the next three years.

There has been success previously in reversing type 1 diabetes in humans; however there would not be enough islet cells available for transplantation to treat the number of people that need the treatment.  The hope is that islet cells from pigs would work.  Diabetic Monkey’s cured with Pig Cells – Possible cure for Diabetes type 1


Premature Birth and Gum Disease Link - Periodontal Ailments Linked to Heart Illness, Early Births and Type 2 Diabetes

Premature Birth and Gum Disease Link - Periodontal Ailments Linked to Heart Illness, Early Births and Type 2 Diabetes

Periodontal Disease

New research reinforces the belief that there is a connection between periodontal disease and cardiovascular disease, as well as premature births.  Now it appears that one way to reduce the risk of heart disease may be to manage other risk factors for the disease as well, including dental hygiene.  Dr. Moise Desyarieux, MD said "It appears a relationship exists, but we don't know exactly what it is and if it is a causal relationship.  Therefore, we can't make recommendations for people with periodontal disease in respect to cardiovascular disease." 

Dr. Desvarieux is an infectious disease epidemiologist in the Department of Epidemiology at Columbia University's Mailman School of Public Health.  His team coordinated the (INVEST) study to investigate the oral health-cardiovascular disease relationship.

The main risk factors for cardiovascular disease should also be addressed.  Dr. Desvarieux said "To reduce their risk for cardiovascular disease, patients must manage all their risk factors, including smoking, diabetes, and weight."  Premature Birth and Gum Disease Link - Periodontal Ailments Linked to Heart Illness, Early Births and Type 2 Diabetes  


Diabetes Eye Health improved with a Marijuana compound that Helps Stops Diabetic Retinopathy and Blindness

Diabetes Eye Health improved with a Marijuana compound that Helps Stops Diabetic Retinopathy and Blindness

Eye that is damaged by diabetic retinopathy

Diabetic patients are often threatened with damage to eyes and blindness. Researchers believe that cannabidiol, a compound that comes from Marijuana plants may help to stop the damaging retinopathy by slowing the growth of leaky blood vessels.  The cannabidiol compound does not get a person intoxicated but in the future may be able to help over 16 million Americans that have Diabetic retinopathy from becoming blind.

Dr. Gregory I. Liou who is a molecular biologist at the Medical College of Georgia and fellow researchers has received a $300,000 grant from the American Diabetes Association hope to help treat diabetic retinopathy.  "We are studying the role of cannabinoid receptors in our body and trying to modulate them so we can defend against diabetic retinopathy," Dr. Liou said. Diabetes Eye Health improved with a Marijuana compound that Helps Stops Diabetic Retinopathy and Blindness


Embryonic Stem Cell Treatments Show Promise for Degenerative Diseases and Paralysis - Alzheimer's Parkinson's Cancer Heart Disease and More

Embryonic Stem Cell Treatments Show Promise for Degenerative Diseases and Paralysis - Alzheimer's Parkinson's Cancer Heart Disease and More

Embryonic Stem Cells

Stem cell research and treatment may yield extraordinary results for ailments including heart disease, Parkinson’s disease, cancer and diabetes.  Embryonic stem cells also show promise for people that are paralyzed. 

The CBS News program 60 minutes ran a segment on the subject Sunday night.  Ed Bradley’s report included an interview with Dr. Hans Keirstead, a 38-year-old biologist, who said he is ready to try a stem cell procedure on people paralyzed by spinal cord injuries.  The doctor’s earlier trial showed success in treating a laboratory rat whose hind legs were completely paralyzed. 

Amazingly, after injecting the rat with human embryonic stem cells, the paralyzed rat was able to move its hind legs.  Dr. Keirstead told Mr. Bradley that “If it does the same thing in humans, I think we’ve hit something here that’s gonna be truly remarkable."  He hopes to begin clinical trials on patients that have recently been paralyzed first.  Embryonic Stem Cell Treatments Show Promise for Degenerative Diseases and Paralysis - Alzheimer's Parkinson's Cancer Heart Disease and More


Pritikin Diet and Exercise Program helped treat Type II Diabetes and Metabolic Syndrome in Obese and Overweight Patients

Pritikin Diet and Exercise Program helped treat Type II Diabetes and Metabolic Syndrome in Obese and Overweight Patients

Pritikin Weight Loss Book

A recent study published in the online edition of the Journal of Applied Physiology, showed a 50 percent reversal in people with metabolic syndrome, Type 2 diabetes by following the Pritikin diet and exercise program over a 3 week period of time.

The lead researcher, Christian Roberts, from the University of California, Los Angeles said, "The study shows, contrary to common belief, that Type 2 diabetes and metabolic syndrome can be reversed solely through lifestyle changes."

"This regimen reversed a clinical diagnosis of Type 2 diabetes or metabolic syndrome in about half the participants who had either of those conditions. However, the regimen may not have reversed damage such as plaque development in the arteries," Roberts said. "However, if Type 2 diabetes and metabolic syndrome continue to be controlled, further damage would likely be minimized and it's plausible that continuing to follow the program long-term may result in reversal of atherosclerosis."   Pritikin Diet and Exercise Program helped treat Type II Diabetes and Metabolic Syndrome in Obese and Overweight Patients


Obesity Doubles Childs Risk of Diabetes - Study Found Half of the Children are Twice as likely to become Diabetic

Obesity Doubles Childs Risk of Diabetes - Study Found Half of the Children are Twice as likely to become Diabetic

Kaufman's Book

A new study says that overweight children are twice as likely to develop diabetes as normal weight children.  Although few children in the study had diabetes, their risk factors were “very high”. 

The study included 1,740 eighth-graders from 12 U.S. schools.  They found that half of the children were either overweight or on the verge of becoming overweight.  Being overweight is one of the primary risk factors for type-2 diabetes. 

Of these children, 41 percent had elevated blood sugar levels and 36 percent had high levels of insulin.  Insulin is a hormone that helps process blood sugar.  High insulin and blood sugar levels signal that the body is becoming resistant to insulin.  This is a precursor to type-2 diabetes.  These tests were taken after fasting.  Obesity Doubles Childs Risk of Diabetes - Study Found Half of the Children are Twice as likely to become Diabetic


Exubera Inhaled Insulin Expected to be Available Soon for Diabetes Treatment

Exubera Inhaled Insulin Expected to be Available Soon for Diabetes Treatment

Exubera Inhaler

The Food and Drug Administration (FDA) approved the first inhaled form of insulin on Friday.  This method of intake is easier than injections and gives millions of adult diabetics an alternative to the older form of administering insulin.  Americans can expect to see this on the market by midyear.

Exubera, developed by Nektar Therapeutics, is a powder form of recombinant human insulin (rDNA) for treating adults with type 1 and type 2 diabetes.  According to an FDA press release, this is the first “insulin delivery option introduced since the discovery of insulin in the 1920s.”

Dr. Steven Galson, Director of the Center for Drug Evaluation and Research for the FDA said "It is our hope that the availability of inhaled insulin will offer patients more options to better control their blood sugars."  Exubera Inhaled Insulin Expected to be Available Soon for Diabetes Treatment

Work Related Stress Linked to Heart Disease and Diabetes  - British Journal of Medicine

Work Related Stress Linked to Heart Disease and Diabetes  - British Journal of Medicine

Stress at work

Stress at work can lead to a metabolic syndrome that causes heart disease and diabetes, according to researchers at the University College London.  The exact causes are unclear but there is new evidence for the “biological plausibility” link between work stress and heart disease.

The researchers looked at 10,308 British civil servants between the ages of 35 and 55 over a 14 year period.  They measured work stress four times between 1985 and 1999 and they also measured risk factors for the metabolic syndrome between 1997 and 1999.  These risk factors include obesity, high blood pressure and high cholesterol.  The researchers also took into account social position, smoking, heavy alcohol consumption and lack of exercise.  Work Related Stress Linked to Heart Disease and Diabetes  - British Journal of Medicine  


Saturated Fat Overload causes Cells to Die – Increased risk for Diabetes

Saturated Fat Overload causes Cells to Die – Increased risk for Diabetes

measuring body fat

Researchers at Washington University School of Medicine in St. Louis say that too much saturated fat spurs a protein to kill mammalian cells. 

The researchers were able to stop the production of the protein called EF1 A-1 which thrives with high levels of saturated fat palmitate.  When the production of the protein was stopped, it slowed the cell death.  If the cell was abundant with the palmitate fat, the cells would produce the EF1 A-1 protein and this caused these cells to die rapidly.  Saturated Fat Overload causes Cells to Die – Increased risk for Diabetes


Dry Skin Treatment for Diabetics

Dry Skin Treatment for Diabetics

Skin MD

Skin problems and diabetes are so closely associated that diabetes is often first diagnosed by dermatologists. Several changes to the skin, including boils, blisters called ‘diabetic bullae’, skin tags, dark skin around the neck and fingers, and dry skin, indicate the possibility of diabetes.

What is diabetes and how does it cause skin problems? Many think diabetes is the result of eating too much sugar. In fact, it is a problem with the immune system. In a healthy body, specialized cells (called beta cells) manufacture insulin in the pancreas. Insulin is a hormone responsible for transporting glucose to the cells. The body then burns the glucose, creating carbon dioxide, water and energy. The body cannot maintain a healthy condition without this process. In type one diabetes, the immune system attacks beta cells – mistaking them for invaders. In type two diabetes, insulin is still manufactured, but in quantities below.
  Dry Skin Treatment for Diabetics


Heart Disease can be caused by Stress

Heart Disease can be caused by Stress

Blood Pressure monitor

A recent study published in Psychophysiology confirms that mental stress raises blood pressure and also causes negative emotions in the brains regions which cause a physical response to the whole body.

Because of the activity in the cingulated cortex while the person is having mental stress it may cause their blood pressure to rise and this puts the individual at a higher risk for heart disease.  Heart Disease can be caused by Stress

 


Type-2 Diabetes Treatment my include Managing an Enzyme

Type-2 Diabetes Treatment my include Managing an Enzyme

Insulin Molecule

There is a link between high-fat diets and type 2 diabetes, according to researchers at the University of California, San Diego.  In fact they have found a molecular connection between the fat and the disruption of insulin production. 

An enzyme called GnT-4a enables the beta cells in the pancreas to monitor blood glucose levels and produce the appropriate amount of insulin.  The study appearing in the December 29th issue of the journal Cell examined how this enzyme is suppressed by a high-fat diet in mice.  The result of the high-fat diet is diabetes.

In the early stages of diabetes patients produce insufficient amounts of insulin resulting in hyperglycemia.  Hyperglycemia is an elevated level of blood glucose in the blood.  The Beta cells overcompensate and produce too much insulin, resulting in diabetes.  Type-2 Diabetes Treatment my include Managing an Enzyme


Diabetics can cut Risk of Heart Attack and Stroke by increasing Insulin Injections

Diabetics can cut Risk of Heart Attack and Stroke by increasing Insulin Injections

Blood Sugar Testing

Researchers have found that increasing the number in insulin injections per day will substantially reduce the risk of cardiovascular disease in Type 1 diabetes patients.  Cardiovascular disease is one of the deadliest complications of the condition. 

The risk of heart disease is 10 times greater in people with type 1 diabetes.  The good news is that aggressively controlling blood sugar by increasing the number of injections a day will cut the risk  of heart attack in half.  Most diabetics will inject themselves once or twice a day.  Aggressive control would mean five or six injections a day.

Dr. Saul M Genuth, chairman of a research project initiated in 1983 said "When you bring your blood glucose as close to normal as possible, that is what counts most,” reports Newsday.  The first trial ended in 1993 and included 1,441 type 1 patients.  Diabetics can cut Risk of Heart Attack and Stroke by increasing Insulin Injections


Alzheimer’s Disease could be Caused by a New Type 3 Diabetes

Alzheimer’s Disease could be Caused by a New Type 3 Diabetes

Alzheimer's Diabetes Link

Researchers may see a connection between diabetes and Alzheimer’s disease.  In fact, according to researchers, Alzheimer’s may be a third type of diabetes.  The researchers examined insulin and the insulin receptor function in an area of the brain affected by Alzheimer’s disease.

The study compared the brain tissues of people who died at various stages of the disease.  Postmortem brain tissue of 45 patients with normal aging or different degrees of Alzheimer’s neurodegeneration, termed “Braak Stages” was examined.

The research conducted at the Rhode Island Hospital and Brown Medical School discovered that the insulin receptors dropped off significantly in the brain even in the early stages of the disease.  The number of receptors continues to drop off as the disease progresses.  Alzheimer’s Disease could be Caused by a New Type 3 Diabetes


Pargluva Drug for Diabetes found to be Dangerous

Pargluva Drug for Diabetes found to be Dangerous

Cost of Diabetes

A new treatment for type-2 diabetes may double the risk of death according to researchers at the Cleveland Clinic.  If the analysis is correct Pargluva (muraglitazar is the generic name), a drug developed by Bristol-Myers Squibb and Merck & Company, could cause a “public health catastrophe”. 

The research was published by the Journal of the American Medical Association.  Muraglitazar is a new drug used to treat both high glucose levels and improve blood lipids.  The drug was approved on October 18th by the Food and Drug Administration (FDA). 

The Journal reports that “in a review of data from Phase 2 and 3 trials conducted by the drug manufacturer and provided to the FDA, Nissen and colleagues found that muraglitazar was associated with an excess incidence of the composite endpoint of death, major adverse cardiovascular events, and congestive heart failure.” Pargluva Drug for Diabetes found to be Dangerous


Health: Diabetes and aging

Dialysis

With a steadily aging society, American health care is in a constant sprint to keep up with the continuing influx of the elderly and their unique needs. One of the needs that appears to have fallen behind in the rush is the care of elderly with diabetes.

With the high amounts of care many diabetics need, the combination of age and the disease can often form a dangerous, if not deadly, combination.  According to a study by the National Diabetes Information Clearinghouse in 2000, 7 million, or 20.1 percent of all people 65 and over have diabetes.

Those numbers promises to grow dramatically in the future.  How the elderly cope with the strain of diabetes is varied. Some get in-house nursing; a nurse to come in daily to administer insulin shots.

Others rely heavily on support of their grown children or other family members, while other stay independent and take care of themselves Marilyn Shankar, a Diabetes Educator for Health Educators Medical Group in San Bernardino, Calif., said that the type of care an elderly person gets depends on the person’s personality.  Health: Diabetes and aging


Gene Discovery may Lead to Obesity Treatment

Gene Discovery may Lead to Obesity Treatment

Gene Discovery

Research out of the Duke Medical Center may shed light on why it is so hard to keep weight off after dieting.  It was found that skeletal muscle tissue and cells from obese people were programmed to store fat even when removed from the body and forced to grow in the laboratory.

Dr Deborah Duoio found that an accumulation of intramuscular lipids called SCD1 (Stearoyl-CoA Desaturase-1) becomes over-expressed in obese women.  The increase of the gene SCD1 starts a cascade of cellular events culminating in increased fat storage in muscle tissue.  This may be the key reason why dieting fails.  Gene Discovery may Lead to Obesity Treatment


Cures for interfering RNAi may be around the Corner

Cures for interfering RNAi may be around the Corner

RNA Interference

It is becoming more evident each day that your DNA has a lot to with the diseases you get, including cancer, diabetes, and Alzheimer's.  Scientists have always wondered if there was a way to change your genes to prevent these illnesses. 

One of the more exciting avenues in this study is RNA interference (or RNAi).  During the 1990's, scientists realized the power of the RNAi technique to determine gene function by blocking the expression of a specific mRNAs. 

The silencing (or interference) occurs when an organism (like a human) is injected with an RNA sequence that is complementary to the mRNA transcribed from the target gene.  The interference will block the production of an encoded protein.  This may be a process to correct many genetic defects. Cures for interfering RNAi may be around the Corner


SEPS1 Gene Discovered Regulates Inflammation in Humans

SEPS1 Gene Discovered Regulates Inflammation in Humans

Cell Inflammation

Researchers in the U.S. and Australia have discovered a gene that regulates inflammation.  They accessed the role of genetic variations in the selenoprotein S (SEPS1, also called SELS or SELENOS), a gene involved in stress response in the endoplasmic reticulum and inflammation control.

This could have far-reaching implications because inflammation has been shown to have an underlying role in cancer, cardiovascular disease, diabetes, obesity and Alzheimer’s diseases.  It has been reported that the research could lead to a therapy in two to four years.  RNA interference could play a role in therapy.  SEPS1 Gene Discovered Regulates Inflammation in Humans


Biophiltre uses Nano-Technology to make Portable Kidney Dialysis

Biophiltre uses Nano-Technology to make Portable Kidney Dialysis

Kidney

Kidney failure may have a new treatment soon with newly emerging nano-technology.  A nano-technology startup company called Biophiltre is developing a filter that will copy the functions of the kidney. 

The artificial device would be made up of 2 membranes; one call the G would copy the function of the glomerulus, the other is called the T, which will mimic the renal tubule.  The glomerulus is the part of the kidney that filters the blood leaving water as a byproduct.  The Renal tubule function is to a recycling center to reclaim compounds that need to be reused.  Biophiltre uses Nano-Technology to make Portable Kidney Dialysis

 

 

 

 
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Copyright 2005 Best Syndication                                            Last Updated Sunday, July 11, 2010 01:18 AM